PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mi...

Por Huang, Na, Lu, Shuai, Liu, Xiao-Ge, Zhu, Jie, Wang, Yu-Jiong, Liu, Rui-Tian
Publicado no Oncotarget (2017)

Activated Scavenger Receptor A Promotes Glial Internalization of Aβ

Por Zhang, He, Su, Ya-jing, Zhou, Wei-wei, Wang, Shao-wei, Xu, Peng-xin, Yu, Xiao-lin, Liu, Rui-tian
Publicado em 2014

Interleukin-1β-Targeted Vaccine Improves Glucose Control and β-Cell Function in a Diabetic KK-A(y) Mouse Model

Por Zha, Jun, Chi, Xiao-wei, Yu, Xiao-lin, Liu, Xiang-meng, Liu, Dong-qun, Zhu, Jie, Ji, Hui, Liu, Rui-tian
Publicado no PLoS One (2016)

A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses

Por Zha, Jun, Liu, Xiang-meng, Zhu, Jie, Liu, Shu-ying, Lu, Shuai, Xu, Peng-xin, Yu, Xiao-lin, Liu, Rui-tian
Publicado no Sci Rep (2016)

Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Al...

Por Ji, Mei, Xie, Xi-xiu, Liu, Dong-qun, Yu, Xiao-lin, Zhang, Yue, Zhang, Ling-Xiao, Wang, Shao-wei, Huang, Ya-ru, Liu, Rui-tian
Publicado no Alzheimers Res Ther (2018)

A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease

Por Wang, Shao-wei, Liu, Dong-qun, Zhang, Ling-xiao, Ji, Mei, Zhang, Yang-xin, Dong, Quan-xiu, Liu, Shu-ying, Xie, Xi-xiu, Liu, Rui-tian
Publicado no Alzheimers Res Ther (2017)

A Peptide Binding to the β-Site of APP Improves Spatial Memory and Attenuates Aβ Burden in Alzheimer’s Disease Transgenic Mice

Por Yang, Shi-gao, Wang, Shao-wei, Zhao, Min, Zhang, Ran, Zhou, Wei-wei, Li, Ya-nan, Su, Ya-jing, Zhang, He, Yu, Xiao-lin, Liu, Rui-tian
Publicado em 2012