Tubulin acetyltransferase discovered: Ciliary role in the ancestral eukaryote expanded to neurons in metazoans

Por Leroux, Michel R.
Publicado em 2010

The roles of evolutionarily conserved functional modules in cilia-related trafficking

Por Sung, Ching-Hwa, Leroux, Michel R.
Publicado em 2013

Getting a grip on non-native proteins

Por Stirling, Peter C., Lundin, Victor F., Leroux, Michel R.
Publicado em 2003

The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

Por Reiter, Jeremy F, Blacque, Oliver E, Leroux, Michel R
Publicado em 2012

Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron

Por Nguyen, Phuong Anh T., Liou, Willisa, Hall, David H., Leroux, Michel R.
Publicado no J Cell Sci (2014)

Functional Interaction between Phosducin-like Protein 2 and Cytosolic Chaperonin Is Essential for Cytoskeletal Protein Function and Cell Cycle Progression

Por Stirling, Peter C., Srayko, Martin, Takhar, Karam S., Pozniakovsky, Andrei, Hyman, Anthony A., Leroux, Michel R.
Publicado em 2007

Mutations in a Guanylate Cyclase GCY-35/GCY-36 Modify Bardet-Biedl Syndrome–Associated Phenotypes in Caenorhabditis elegans

Por Mok, Calvin A., Healey, Michael P., Shekhar, Tanvi, Leroux, Michel R., Héon, Elise, Zhen, Mei
Publicado em 2011

Ciliogenesis in Caenorhabditis elegans requires genetic interactions between ciliary middle segment localized NPHP-2 (inversin) and transition zone-associated proteins

Por Warburton-Pitt, Simon R. F., Jauregui, Andrew R., Li, Chunmei, Wang, Juan, Leroux, Michel R., Barr, Maureen M.
Publicado em 2012

Formation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP(2) ciliary abun...

Por Jensen, Victor L, Li, Chunmei, Bowie, Rachel V, Clarke, Lara, Mohan, Swetha, Blacque, Oliver E, Leroux, Michel R
Publicado no EMBO J (2015)

Observation of the noncovalent assembly and disassembly pathways of the chaperone complex MtGimC by mass spectrometry

Por Fändrich, Marcus, Tito, Mark A., Leroux, Michel R., Rostom, Adam A., Hartl, F. Ulrich, Dobson, Christopher M., Robinson, Carol V.
Publicado em 2000

Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin

Por Lundin, Victor F., Stirling, Peter C., Gomez-Reino, Juan, Mwenifumbo, Jill C., Obst, Jennifer M., Valpuesta, José M., Leroux, Michel R.
Publicado em 2004

Caenorhabditis elegans DYF-2, an Orthologue of Human WDR19, Is a Component of the Intraflagellar Transport Machinery in Sensory Cilia

Por Efimenko, Evgeni, Blacque, Oliver E., Ou, Guangshuo, Haycraft, Courtney J., Yoder, Bradley K., Scholey, Jonathan M., Leroux, Michel R., Swoboda, Peter
Publicado em 2006

The WD Repeat-containing Protein IFTA-1 Is Required for Retrograde Intraflagellar Transport

Por Blacque, Oliver E., Li, Chunmei, Inglis, Peter N., Esmail, Muneer A., Ou, Guangshuo, Mah, Allan K., Baillie, David L., Scholey, Jonathan M., Leroux, Michel R.
Publicado em 2006

Sensory Ciliogenesis in Caenorhabditis elegans: Assignment of IFT Components into Distinct Modules Based on Transport and Phenotypic Profiles

Por Ou, Guangshuo, Koga, Makato, Blacque, Oliver E., Murayama, Takashi, Ohshima, Yasumi, Schafer, Jenny C., Li, Chunmei, Yoder, Bradley K., Leroux, Michel R., Scholey, Jonathan M.
Publicado em 2007

Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors

Por Pan, Xiaoyu, Ou, Guangshuo, Civelekoglu-Scholey, Gul, Blacque, Oliver E., Endres, Nicholas F., Tao, Li, Mogilner, Alex, Leroux, Michel R., Vale, Ronald D., Scholey, Jonathan M.
Publicado em 2006

The interaction network of the chaperonin CCT

Por Dekker, Carien, Stirling, Peter C, McCormack, Elizabeth A, Filmore, Heather, Paul, Angela, Brost, Renee L, Costanzo, Michael, Boone, Charles, Leroux, Michel R, Willison, Keith R
Publicado em 2008

Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling

Por Yee, Laura E., Garcia-Gonzalo, Francesc R., Bowie, Rachel V., Li, Chunmei, Kennedy, Julie K., Ashrafi, Kaveh, Blacque, Oliver E., Leroux, Michel R., Reiter, Jeremy F.
Publicado no PLoS Genet (2015)

Bardet-Biedl Syndrome-associated Small GTPase ARL6 (BBS3) Functions at or near the Ciliary Gate and Modulates Wnt Signaling

Por Wiens, Cheryl J., Tong, Yufeng, Esmail, Muneer A., Oh, Edwin, Gerdes, Jantje M., Wang, Jihong, Tempel, Wolfram, Rattner, Jerome B., Katsanis, Nicholas, Park, Hee-Won, Leroux, Michel R.
Publicado em 2010

Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport

Por Phirke, Prasad, Efimenko, Evgeni, Mohan, Swetha, Burghoorn, Jan, Crona, Filip, Bakhoum, Mathieu W., Trieb, Maria, Schuske, Kim, Jorgensen, Erik M., Piasecki, Brian P., Leroux, Michel R., Swoboda, Peter
Publicado em 2011

Localization of a Guanylyl Cyclase to Chemosensory Cilia Requires the Novel Ciliary MYND Domain Protein DAF-25

Por Jensen, Victor L., Bialas, Nathan J., Bishop-Hurley, Sharon L., Molday, Laurie L., Kida, Katarzyna, Nguyen, Phuong Anh T., Blacque, Oliver E., Molday, Robert S., Leroux, Michel R., Riddle, Donald L.
Publicado em 2010