Subjects with Molecularly Defined Familial Hypercholesterolemia or Familial Defective apoB-100 Are Not Being Adequately Treated

Por Leren, Trond P., Berge, Knut Erik
Publicado em 2011

Genetic testing in specific cardiomyopathies

Por Haugaa, Kristina Hermann, Leren, Trond P, Amlie, Jan Peder
Publicado em 2009

Variable phenotypic expression of nonsense mutation p.Thr5* in the APOE gene

Por Leren, Trond P., Strøm, Thea Bismo, Berge, Knut Erik
Publicado no Mol Genet Metab Rep (2016)

Studies of the autoinhibitory segment comprising residues 31–60 of the prodomain of PCSK9: Possible implications for the mechanism underlying gain-of-function mutations

Por Wierød, Lene, Cameron, Jamie, Strøm, Thea Bismo, Leren, Trond P.
Publicado no Mol Genet Metab Rep (2016)

PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment

Por Tveten, Kristian, Strøm, Thea Bismo, Berge, Knut Erik, Leren, Trond P.
Publicado em 2013

Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reti...

Por Strøm, Thea Bismo, Tveten, Kristian, Laerdahl, Jon K., Leren, Trond P.
Publicado em 2014

Degradation of the LDL receptors by PCSK9 is not mediated by a secreted protein acted upon by PCSK9 extracellularly

Por Holla, Øystein L, Cameron, Jamie, Berge, Knut Erik, Ranheim, Trine, Leren, Trond P
Publicado em 2007

Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long QT syndrome

Por Haugaa, Kristina Hermann, Edvardsen, Thor, Leren, Trond P., Gran, Jon Michael, Smiseth, Otto A., Amlie, Jan P.
Publicado em 2009

Results of comprehensive diagnostic work-up in ‘idiopathic’ dilated cardiomyopathy

Por Broch, Kaspar, Andreassen, Arne K, Hopp, Einar, Leren, Trond P, Scott, Helge, Müller, Fredrik, Aakhus, Svend, Gullestad, Lars
Publicado no Open Heart (2015)

Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors

Por Holla, Øystein L., Cameron, Jamie, Tveten, Kristian, Strøm, Thea Bismo, Berge, Knut Erik, Laerdahl, Jon K., Leren, Trond P.
Publicado em 2011

Mortality Among Patients With Familial Hypercholesterolemia: A Registry‐Based Study in Norway, 1992–2010

Por Mundal, Liv, Sarancic, Mirza, Ose, Leiv, Iversen, Per Ole, Borgan, Jens‐Kristian, Veierød, Marit B., Leren, Trond P., Retterstøl, Kjetil
Publicado no J Am Heart Assoc (2014)

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

Por Holst, Anders G., Calloe, Kirstine, Jespersen, Thomas, Cedergreen, Pernille, Winkel, Bo G., Jensen, Henrik Kjaerulf, Leren, Trond P., Haunso, Stig, Svendsen, Jesper Hastrup, Tfelt-Hansen, Jacob
Publicado em 2009

Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

Por Christiansen, Michael, Hedley, Paula L, Theilade, Juliane, Stoevring, Birgitte, Leren, Trond P, Eschen, Ole, Sørensen, Karina M, Tybjærg-Hansen, Anne, Ousager, Lilian B, Pedersen, Lisbeth N, Frikke-Schmidt, Ruth, Aidt, Frederik H, Hansen, Michael G, Hansen, Jim, Bloch Thomsen, Poul E, Toft, Egon, Henriksen, Finn L, Bundgaard, Henning, Jensen, Henrik K, Kanters, Jørgen K
Publicado em 2014

Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody

Por Hopkins, Paul N., Defesche, Joep, Fouchier, Sigrid W., Bruckert, Eric, Luc, Gérald, Cariou, Bertrand, Sjouke, Barbara, Leren, Trond P., Harada-Shiba, Mariko, Mabuchi, Hiroshi, Rabès, Jean-Pierre, Carrié, Alain, van Heyningen, Charles, Carreau, Valérie, Farnier, Michel, Teoh, Yee P., Bourbon, Mafalda, Kawashiri, Masa-aki, Nohara, Atsushi, Soran, Handrean, Marais, A. David, Tada, Hayato, Abifadel, Marianne, Boileau, Catherine, Chanu, Bernard, Katsuda, Shoji, Kishimoto, Ichiro, Lambert, Gilles, Makino, Hisashi, Miyamoto, Yoshihiro, Pichelin, Matthieu, Yagi, Kunimasa, Yamagishi, Masakazu, Zair, Yassine, Mellis, Scott, Yancopoulos, George D., Stahl, Neil, Mendoza, Johanna, Du, Yunling, Hamon, Sara, Krempf, Michel, Swergold, Gary D.
Publicado no Circ Cardiovasc Genet (2015)