Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells

Por Hu, Kaiji, Law, Jennifer H, Fotovati, Abbas, Dunn, Sandra E
Publicado em 2012

Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK)

Por Santos, Nancy Dos, Habibi, Golareh, Wang, Michelle, Law, Jennifer H., Andrews, Heather N., Wei, Daniel, Triche, Timothy, Dedhar, Shoukat, Dunn, Sandra E.
Publicado em 2007

Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes

Por Habibi, Golareh, Leung, Samuel, Law, Jennifer H, Gelmon, Karen, Masoudi, Hamid, Turbin, Dmitry, Pollak, Michael, Nielsen, Torsten O, Huntsman, David, Dunn, Sandra E
Publicado em 2008

Molecular Decoy to the Y-Box Binding Protein-1 Suppresses the Growth of Breast and Prostate Cancer Cells whilst Sparing Normal Cell Viability

Por Law, Jennifer H., Li, Yvonne, To, Karen, Wang, Michelle, Astanehe, Arezoo, Lambie, Karen, Dhillon, Jaspreet, Jones, Steven J. M., Gleave, Martin E., Eaves, Connie J., Dunn, Sandra E.
Publicado em 2010

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)

Por Reipas, Kristen M., Law, Jennifer H., Couto, Nicole, Islam, Sumaiya, Li, Yvonne, Li, Huifang, Cherkasov, Artem, Jung, Karen, Cheema, Amarpal S., Jones, Steven J.M., Hassell, John A., Dunn, Sandra E.
Publicado em 2013

YB-1 induces expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance

Por To, Karen, Fotovati, Abbas, Reipas, Kristen M., Law, Jennifer H., Hu, Kaiji, Wang, Jing, Astanehe, Arezoo, Davies, Alastair H., Lee, Lawrence, Stratford, Anna L., Raouf, Afshin, Johnson, Pauline, Berquin, Isabelle M., Royer, Hans-Dieter, Eaves, Connie J., Dunn, Sandra E.
Publicado em 2010