Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria

Por Darpo, Borje, Ferber, Georg, Siegl, Peter, Laurijssens, Bart, Macintyre, Fiona, Toovey, Stephen, Duparc, Stephan
Publicado no Br J Clin Pharmacol (2015)

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects

Por Ali, Zahid, Laurijssens, Bart, Ostenfeld, Thor, McHugh, Simon, Stylianou, Anastasia, Scott-Stevens, Paul, Hosking, Louise, Dewit, Odile, Richardson, Jill C, Chen, Chao
Publicado em 2013

Prolonged pharmacodynamic effects of S-0139, an intravenously administered endothelin A (ET(A)) antagonist, in the human forearm blood flow model

Por Lunnon, Martin W, Wallace, Sharon M L, Palmer, Joanne E, Francis-Lang, Andrew, Laurijssens, Bart E, Mistry, Prafull, Albala, Bruce, Nagafuji, Toshiaki, Wilkinson, Ian B, Maltby, Kay
Publicado em 2010

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquin...

Por Macintyre, Fiona, Adoke, Yeka, Tiono, Alfred B., Duong, Tran Thanh, Mombo-Ngoma, Ghyslain, Bouyou-Akotet, Marielle, Tinto, Halidou, Bassat, Quique, Issifou, Saadou, Adamy, Marc, Demarest, Helen, Duparc, Stephan, Leroy, Didier, Laurijssens, Bart E., Biguenet, Sophie, Kibuuka, Afizi, Tshefu, Antoinette Kitoto, Smith, Melnick, Foster, Chanelle, Leipoldt, Illse, Kremsner, Peter G., Phuc, Bui Quang, Ouedraogo, Alphonse, Ramharter, Michael
Publicado no BMC Med (2017)