Prediction of the structure of the Y+.R-.R(+)-type DNA triple helix by molecular modelling.

Por Laughton, C A, Neidle, S
Publicado em 1992

Atomistic simulations reveal bubbles, kinks and wrinkles in supercoiled DNA

Por Mitchell, J. S., Laughton, C. A., Harris, Sarah A.
Publicado em 2011

DNA minor groove recognition by a tetrahydropyrimidinium analogue of hoechst 33258: NMR and molecular dynamics studies of the complex with d(GGTAATTACC)2.

Por Bostock-Smith, C E, Laughton, C A, Searle, M S
Publicado em 1998

Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents.

Por Laughton, C A, Jenkins, T C, Fox, K R, Neidle, S
Publicado em 1990

Solution structure and dynamics of the A-T tract DNA decamer duplex d(GGTAATTACC)2: implications for recognition by minor groove binding drugs.

Por Bostock-Smith, C E, Laughton, C A, Searle, M S
Publicado em 1999

Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.

Por Kao, Y C, Zhou, C, Sherman, M, Laughton, C A, Chen, S
Publicado em 1998

Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA).

Por Bates, P J, Dosanjh, H S, Kumar, S, Jenkins, T C, Laughton, C A, Neidle, S
Publicado em 1995

Efficient triple helix formation by oligodeoxyribonucleotides containing alpha- or beta-2-amino-5-(2-deoxy-D-ribofuranosyl) pyridine residues.

Por Bates, P J, Laughton, C A, Jenkins, T C, Capaldi, D C, Roselt, P D, Reese, C B, Neidle, S
Publicado em 1996

Characteristics of triplex-directed photoadduct formation by psoralen-linked oligodeoxynucleotides.

Por Bates, P J, Macaulay, V M, McLean, M J, Jenkins, T C, Reszka, A P, Laughton, C A, Neidle, S
Publicado em 1995

Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines

Por Mohammed, M Z, Vyjayanti, V N, Laughton, C A, Dekker, L V, Fischer, P M, Wilson, D M, Abbotts, R, Shah, S, Patel, P M, Hickson, I D, Madhusudan, S
Publicado em 2011

The fitness burden imposed by synthesising quorum sensing signals

Por Ruparell, A., Dubern, J. F., Ortori, C. A., Harrison, F., Halliday, N. M., Emtage, A., Ashawesh, M. M., Laughton, C. A., Diggle, S. P., Williams, P., Barrett, D. A., Hardie, K. R.
Publicado no Sci Rep (2016)