Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem Cells

Por Iya Prytkova, Iya Prytkova, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand
Publicado em 2017-11-01

The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening

Por David M. Gonzalez, David M. Gonzalez, David M. Gonzalez, Jill Gregory, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand
Publicado em 2017-12-01

GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis

Por Yuji Kajiwara, Erming Wang, Minghui Wang, Wun Chey Sin, Kristen J. Brennand, Eric Schadt, Christian C. Naus, Joseph Buxbaum, Bin Zhang
Publicado em 2018-12-01

Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes

Por Seok-Man Ho, Brigham J. Hartley, Erin Flaherty, Prashanth Rajarajan, Rawan Abdelaal, Ifeanyi Obiorah, Natalie Barretto, Hamza Muhammad, Hemali P. Phatnani, Schahram Akbarian, Kristen J. Brennand
Publicado em 2017-08-01

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

Por Lorna A. Farrelly, Shuangping Zheng, Nadine Schrode, Aaron Topol, Natarajan V. Bhanu, Ryan M. Bastle, Aarthi Ramakrishnan, Jennifer C Chan, Bulent Cetin, Erin Flaherty, Li Shen, Kelly Gleason, Carol A. Tamminga, Benjamin A. Garcia, Haitao Li, Kristen J. Brennand, Ian Maze
Publicado em 2022-04-01

A Role for Noncoding Variation in Schizophrenia

Por Panos Roussos, Amanda C. Mitchell, Georgios Voloudakis, John F. Fullard, Venu M. Pothula, Jonathan Tsang, Eli A. Stahl, Anastasios Georgakopoulos, Douglas M. Ruderfer, Alexander Charney, Yukinori Okada, Katherine A. Siminovitch, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Robert M. Plenge, Soumya Raychaudhuri, Menachem Fromer, Shaun M. Purcell, Kristen J. Brennand, Nikolaos K. Robakis, Eric E. Schadt, Schahram Akbarian, Pamela Sklar
Publicado em 2014-11-01