Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission

Por Dechering, Koen J., Duerr, Hans-Peter, Koolen, Karin M. J., Gemert, Geert-Jan van, Bousema, Teun, Burrows, Jeremy, Leroy, Didier, Sauerwein, Robert W.
Publicado no Sci Rep (2017)

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

Por Vos, Martijn W., Stone, Will J. R., Koolen, Karin M., van Gemert, Geert-Jan, van Schaijk, Ben, Leroy, Didier, Sauerwein, Robert W., Bousema, Teun, Dechering, Koen J.
Publicado no Sci Rep (2015)

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

Por Miura, Kazutoyo, Stone, Will J. R., Koolen, Karin M., Deng, Bingbing, Zhou, Luwen, van Gemert, Geert-Jan, Locke, Emily, Morin, Merribeth, Bousema, Teun, Sauerwein, Robert W., Long, Carole A., Dechering, Koen J.
Publicado no Malar J (2016)

Salinomycin and Other Ionophores as a New Class of Antimalarial Drugs with Transmission-Blocking Activity

Por D'Alessandro, Sarah, Corbett, Yolanda, Ilboudo, Denise P., Misiano, Paola, Dahiya, Nisha, Abay, Solomon M., Habluetzel, Annette, Grande, Romualdo, Gismondo, Maria R., Dechering, Koen J., Koolen, Karin M. J., Sauerwein, Robert W., Taramelli, Donatella, Basilico, Nicoletta, Parapini, Silvia
Publicado no Antimicrob Agents Chemother (2015)

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Por Kato, Nobutaka, Comer, Eamon, Sakata-Kato, Tomoyo, Sharma, Arvind, Sharma, Manmohan, Maetani, Micah, Bastien, Jessica, Brancucci, Nicolas M., Bittker, Joshua A., Corey, Victoria, Clarke, David, Derbyshire, Emily R., Dornan, Gillian L., Duffy, Sandra, Eckley, Sean, Itoe, Maurice A., Koolen, Karin M. J., Lewis, Timothy A., Lui, Ping S., Lukens, Amanda K., Lund, Emily, March, Sandra, Meibalan, Elamaran, Meier, Bennett C., McPhail, Jacob A., Mitasev, Branko, Moss, Eli L., Sayes, Morgane, Van Gessel, Yvonne, Wawer, Mathias J., Yoshinaga, Takashi, Zeeman, Anne-Marie, Avery, Vicky M., Bhatia, Sangeeta N., Burke, John E., Catteruccia, Flaminia, Clardy, Jon C., Clemons, Paul A., Dechering, Koen J., Duvall, Jeremy R., Foley, Michael A., Gusovsky, Fabian, Kocken, Clemens H. M., Marti, Matthias, Morningstar, Marshall L., Munoz, Benito, Neafsey, Daniel E., Sharma, Amit, Winzeler, Elizabeth A., Wirth, Dyann F., Scherer, Christina A., Schreiber, Stuart L.
Publicado no Nature (2016)