Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

por Recht, Michael I., Torres, Frank E., De Bruyker, Dirk, Bell, Alan G., Klumpp, Martin, Bruce, Richard H.
Publicado em 2009

Development and validation of a generic fluorescent methyltransferase activity assay based on the Transcreener(®) AMP/GMP Assay

por Klink, Tony A., Staeben, Matt, Twesten, Kim, Kopp, Andrew L., Kumar, Meera, Dunn, Rebecca Schall, Pinchard, Cori A., Kleman-Leyer, Karen M., Klumpp, Martin, Lowery, Robert G.
Publicado em 2011

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

por Chen, Chao, Zhu, Hugh, Stauffer, Frédéric, Caravatti, Giorgio, Vollmer, Susanne, Machauer, Rainer, Holzer, Philipp, Möbitz, Henrik, Scheufler, Clemens, Klumpp, Martin, Tiedt, Ralph, Beyer, Kim S., Calkins, Keith, Guthy, Daniel, Kiffe, Michael, Zhang, Jeff, Gaul, Christoph
Publicado no ACS Med Chem Lett (2016)

PIKfyve, a class III PI-kinase, is the target of the small molecular IL12/23 inhibitor apilimod and a new player in toll-like receptor signaling

por Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N., Wilson, Christopher J., Myer, Vic, Joberty, Gerard, Bouwmeester, Tewis, Labow, Mark A., Finan, Peter M., Porter, Jeffrey A., Ploegh, Hidde L., Baird, Daniel, De Camilli, Pietro, Tallarico, John A., Huang, Qian
Publicado no Chem Biol (2013)