Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

di Recht, Michael I., Torres, Frank E., De Bruyker, Dirk, Bell, Alan G., Klumpp, Martin, Bruce, Richard H.
Pubblicazione 2009

Development and validation of a generic fluorescent methyltransferase activity assay based on the Transcreener(®) AMP/GMP Assay

di Klink, Tony A., Staeben, Matt, Twesten, Kim, Kopp, Andrew L., Kumar, Meera, Dunn, Rebecca Schall, Pinchard, Cori A., Kleman-Leyer, Karen M., Klumpp, Martin, Lowery, Robert G.
Pubblicazione 2011

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

di Chen, Chao, Zhu, Hugh, Stauffer, Frédéric, Caravatti, Giorgio, Vollmer, Susanne, Machauer, Rainer, Holzer, Philipp, Möbitz, Henrik, Scheufler, Clemens, Klumpp, Martin, Tiedt, Ralph, Beyer, Kim S., Calkins, Keith, Guthy, Daniel, Kiffe, Michael, Zhang, Jeff, Gaul, Christoph
Pubblicato in ACS Med Chem Lett (2016)

PIKfyve, a class III PI-kinase, is the target of the small molecular IL12/23 inhibitor apilimod and a new player in toll-like receptor signaling

di Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N., Wilson, Christopher J., Myer, Vic, Joberty, Gerard, Bouwmeester, Tewis, Labow, Mark A., Finan, Peter M., Porter, Jeffrey A., Ploegh, Hidde L., Baird, Daniel, De Camilli, Pietro, Tallarico, John A., Huang, Qian
Pubblicato in Chem Biol (2013)