Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

ανά Recht, Michael I., Torres, Frank E., De Bruyker, Dirk, Bell, Alan G., Klumpp, Martin, Bruce, Richard H.
Έκδοση 2009

Development and validation of a generic fluorescent methyltransferase activity assay based on the Transcreener(®) AMP/GMP Assay

ανά Klink, Tony A., Staeben, Matt, Twesten, Kim, Kopp, Andrew L., Kumar, Meera, Dunn, Rebecca Schall, Pinchard, Cori A., Kleman-Leyer, Karen M., Klumpp, Martin, Lowery, Robert G.
Έκδοση 2011

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

ανά Chen, Chao, Zhu, Hugh, Stauffer, Frédéric, Caravatti, Giorgio, Vollmer, Susanne, Machauer, Rainer, Holzer, Philipp, Möbitz, Henrik, Scheufler, Clemens, Klumpp, Martin, Tiedt, Ralph, Beyer, Kim S., Calkins, Keith, Guthy, Daniel, Kiffe, Michael, Zhang, Jeff, Gaul, Christoph
Τόπος έκδοσης ACS Med Chem Lett (2016)

PIKfyve, a class III PI-kinase, is the target of the small molecular IL12/23 inhibitor apilimod and a new player in toll-like receptor signaling

ανά Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N., Wilson, Christopher J., Myer, Vic, Joberty, Gerard, Bouwmeester, Tewis, Labow, Mark A., Finan, Peter M., Porter, Jeffrey A., Ploegh, Hidde L., Baird, Daniel, De Camilli, Pietro, Tallarico, John A., Huang, Qian
Τόπος έκδοσης Chem Biol (2013)