Urea–hydrogen peroxide prompted the selective and controlled oxidation of thioglycosides into sulfoxides and sulfones

por Singh, Adesh Kumar, Tiwari, Varsha, Mishra, Kunj Bihari, Gupta, Surabhi, Kandasamy, Jeyakumar
Publicado en Beilstein J Org Chem (2017)

Development of generic immunoassay for the detection of a series of aminoglycosides with 6′-OH group for the treatment of genetic diseases in biological samples

por Shalev, Moran, Kandasamy, Jeyakumar, Skalka, Nir, Belakhov, Valery, Rosin-Arbesfeld, Rina, Baasov, Timor
Publicado 2012

Increased Selectivity towards Cytoplasmic versus Mitochondrial Ribosome Confers Improved Efficiency of Synthetic Aminoglycosides in Fixing Damaged Genes: A Strategy for Treatment o...

por Kandasamy, Jeyakumar, Atia-Glikin, Dana, Shulman, Eli, Shapira, Katya, Shavit, Michal, Belakhov, Valery, Baasov, Timor
Publicado 2012

The Designer Aminoglycoside NB84 Significantly Reduces Glycosaminoglycan Accumulation Associated with MPS I-H in the Idua-W392X Mouse

por Wang, Dan, Belakhov, Valery, Kandasamy, Jeyakumar, Baasov, Timor, Li, Su-Chen, Li, Yu-Teh, Bedwell, David M., Keeling, Kim M.
Publicado 2011

Long-Term Nonsense Suppression Therapy Moderates MPS I-H Disease Progression

por Gunn, Gwen, Dai, Yanying, Du, Ming, Belakhov, Valery, Kandasamy, Jeyakumar, Schoeb, Trenton R., Baasov, Timor, Bedwell, David M., Keeling, Kim M.
Publicado 2013

Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites

por Nonaka, Motohiro, Bao, Xingfeng, Matsumura, Fumiko, Götze, Sebastian, Kandasamy, Jeyakumar, Kononov, Andrew, Broide, David H., Nakayama, Jun, Seeberger, Peter H., Fukuda, Minoru
Publicado 2014

Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression

por Keeling, Kim M., Wang, Dan, Dai, Yanying, Murugesan, Srinivasan, Chenna, Balachandra, Clark, Jeremy, Belakhov, Valery, Kandasamy, Jeyakumar, Velu, Sadanandan E., Baasov, Timor, Bedwell, David M.
Publicado 2013

Microbe-focused glycan array screening platform

por Geissner, Andreas, Reinhardt, Anika, Rademacher, Christoph, Johannssen, Timo, Monteiro, João, Lepenies, Bernd, Thépaut, Michel, Fieschi, Franck, Mrázková, Jana, Wimmerova, Michaela, Schuhmacher, Frank, Götze, Sebastian, Grünstein, Dan, Guo, Xiaoqiang, Hahm, Heung Sik, Kandasamy, Jeyakumar, Leonori, Daniele, Martin, Christopher E., Parameswarappa, Sharavathi G., Pasari, Sandip, Schlegel, Mark K., Tanaka, Hidenori, Xiao, Guozhi, Yang, You, Pereira, Claney L., Anish, Chakkumkal, Seeberger, Peter H.
Publicado en Proc Natl Acad Sci U S A (2019)