MET inhibitor tepotinib antagonizes multidrug resistance mediated by ABCG2 transporter: In vitro and in vivo study

Por Zhuo-Xun Wu, Qiu-Xu Teng, Yuqi Yang, Nikita Acharekar, Jing-Quan Wang, Min He, Sabesan Yoganathan, Jun Lin, Jian Wang, Zhe-Sheng Chen
Publicado em 2022-05-01

Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor

Por Yuqi Yang, Ning Ji, Chao‐Yun Cai, Jing‐Quan Wang, Zi‐Ning Lei, Qiu‐Xu Teng, Zhuo‐Xun Wu, Qingbin Cui, Yihang Pan, Zhe‐Sheng Chen
Publicado em 2020-07-01

Microbiota in health and diseases

Por Kaijian Hou, Zhuo-Xun Wu, Xuan-Yu Chen, Jing-Quan Wang, Dongya Zhang, Chuanxing Xiao, Dan Zhu, Jagadish B. Koya, Liuya Wei, Jilin Li, Zhe-Sheng Chen
Publicado em 2022-04-01

Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance

Por Zhuo-Xun Wu, Yuqi Yang, Qiu-Xu Teng, Jing-Quan Wang, Zi-Ning Lei, Jing-Qiu Wang, Sabrina Lusvarghi, Suresh V. Ambudkar, Dong-Hua Yang, Zhe-Sheng Chen
Publicado em 2020-01-01

Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells

Por Xing-Duo Dong, Meng Zhang, Meng Zhang, Xiubin Ma, Jing-Quan Wang, Zi-Ning Lei, Qiu-Xu Teng, Yi-Dong Li, Lusheng Lin, Weiguo Feng, Weiguo Feng, Zhe-Sheng Chen
Publicado em 2020-08-01