Proprietary Algorithms for Polygenic Risk: Protecting Scientific Innovation or Hiding the Lack of It?

le Janssens, A. Cecile J.W.
Foilsithe in Genes (Basel) (2019)

Validity of polygenic risk scores: are we measuring what we think we are?

le Janssens, A Cecile J W
Foilsithe in Hum Mol Genet (2019)

Research Conducted Using Data Obtained through Online Communities: Ethical Implications of Methodological Limitations

le Janssens, A. Cecile J. W., Kraft, Peter
Foilsithe 2012

Novel citation-based search method for scientific literature: application to meta-analyses

le Janssens, A. Cecile J W, Gwinn, M.
Foilsithe in BMC Med Res Methodol (2015)

Erratum to: Novel citation-based search method for scientific literature: application to meta-analyses

le Janssens, A. Cecile J. W., Gwinn, M.
Foilsithe in BMC Med Res Methodol (2015)

Most Published Research Findings Are False—But a Little Replication Goes a Long Way

le Moonesinghe, Ramal, Khoury, Muin J, Janssens, A. Cecile J. W
Foilsithe 2007

Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk

le Kundu, Suman, Kers, Jannigje G., Janssens, A. Cecile J. W.
Foilsithe in PLoS One (2016)

Genetic Scoring Analysis: a way forward in Genome Wide Association Studies?

le Amin, Najaf, van Duijn, Cornelia M., Janssens, A. Cecile J. W.
Foilsithe 2009

How can polygenic inheritance be used in population screening for common diseases?

le Khoury, Muin J., Janssens, A. Cecile J.W., Ransohoff, David F.
Foilsithe in Genet Med (2013)

A tiered-layered-staged model for informed consent in personal genome testing

le Bunnik, Eline M, Janssens, A Cecile J W, Schermer, Maartje H N
Foilsithe 2013

A critical evaluation of the algorithm behind the Relative Citation Ratio (RCR)

le Janssens, A. Cecile J. W., Goodman, Michael, Powell, Kimberly R., Gwinn, Marta
Foilsithe in PLoS Biol (2017)

Evaluation of Polygenic Risk Models Using Multiple Performance Measures: A Critical Assessment of Discordant Results

le Martens, Forike K., Tonk, Elisa C. M., Janssens, A. Cecile J.W.
Foilsithe in Genet Med (2018)

Does Genetic Testing Really Improve the Prediction of Future Type 2 Diabetes?

le Janssens, A. Cecile J. W, Gwinn, Marta, Subramonia-Iyer, Subramony, Khoury, Muin J
Foilsithe 2006

PredictABEL: an R package for the assessment of risk prediction models

le Kundu, Suman, Aulchenko, Yurii S., van Duijn, Cornelia M., Janssens, A. Cecile J. W.
Foilsithe 2011

Novel citation-based search method for scientific literature: a validation study

le Janssens, A. Cecile J. W., Gwinn, Marta, Brockman, J. Elaine, Powell, Kimberley, Goodman, Michael
Foilsithe in BMC Med Res Methodol (2020)

Revisiting the Clinical Validity of Multiplex Genetic Testing in Complex Diseases

le Janssens, A. Cecile J. W., Pardo, M. Carolina, Steyerberg, Ewout W., van Duijn, Cornelia M.
Foilsithe 2004

Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

le Kundu, Suman, Mihaescu, Raluca, Meijer, Catherina M. C., Bakker, Rachel, Janssens, A. Cecile J. W.
Foilsithe 2014

Predictive genetic testing for type 2 diabetes: May raise unrealistic expectations

le Janssens, A Cecile J W, Gwinn, Marta, Valdez, Rodolfo, Narayan, K M Venkat, Khoury, Muin J
Foilsithe 2006

Perspectives on the Use of Multiple Sclerosis Risk Genes for Prediction

le Jafari, Naghmeh, Broer, Linda, van Duijn, Cornelia M., Janssens, A. Cecile J. W., Hintzen, Rogier Q.
Foilsithe 2011

Interpreting Incremental Value of Markers Added to Risk Prediction Models

le Pencina, Michael J., D'Agostino, Ralph B., Pencina, Karol M., Janssens, A. Cecile J. W., Greenland, Philip
Foilsithe 2012