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How can polygenic inheritance be used in population screening for common diseases?
Advances in genomics have near-term impact on diagnosis and management of monogenic disorders. For common complex diseases, the use of genomic information from multiple loci (polygenic model) is generally not useful for diagnosis and individual prediction. In principle, the polygenic model could be...
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| Publicado no: | Genet Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692802/ https://ncbi.nlm.nih.gov/pubmed/23412608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2012.182 |
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