The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2(Arg)439(His) knockin mouse

Por Jacobsen, Jacob P. R., Medvedev, Ivan O., Caron, Marc G.
Publicado em 2012

Adjunctive 5-hydroxytryptophan slow-release for treatment-resistant depression: Clinical and pre-clinical rationale

Por Jacobsen, Jacob P.R., Krystal, Andrew D., Krishnan, K. Ranga R., Caron, Marc G.
Publicado no Trends Pharmacol Sci (2016)

Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action

Por Urs, Nikhil M., Snyder, Joshua C., Jacobsen, Jacob P. R., Peterson, Sean M., Caron, Marc G.
Publicado em 2012

Tryptophan Hydroxylase 2 Genotype Determines Brain Serotonin Synthesis but Not Tissue Content in C57Bl/6 and BALB/c Congenic Mice

Por Siesser, William B., Zhang, Xiaodong, Jacobsen, Jacob P.R., Sotnikova, Tatyana D., Gainetdinov, Raul R., Caron, Marc G.
Publicado em 2010

Cerebral 5-HT(2A) receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

Por Jørgensen, Christinna V, Jacobsen, Jacob P, Caron, Marc G, Klein, Anders Bue, Knudsen, Gitte M, Mikkelsen, Jens D
Publicado no Neurosci Lett (2013)

The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress

Por Sachs, Benjamin D., Rodriguiz, Ramona M., Siesser, William B., Kenan, Alexander, Royer, Elizabeth L., Jacobsen, Jacob P. R., Wetsel, William C., Caron, Marc G.
Publicado em 2013

The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse

Por Jacobsen, Jacob P.R., Plenge, Per, Sachs, Benjamin D., Pehrson, Alan L., Cajina, Manuel, Du, Yunzhi, Roberts, Wendy, Rudder, Meghan L., Dalvi, Prachiti, Robinson, Taylor J., O’Neill, Sharon P., Khoo, King S., Morillo, Connie Sanchez, Zhang, Xiaodong, Caron, Marc G.
Publicado no Psychopharmacology (Berl) (2014)