Decitabine Increases Fetal Hemoglobin in P. Anubis by Increasing γ-globin Gene Transcription

Por Akpan, Imo, Banzon, Virryan, Ibanez, Vinzon, Vaitkus, Kestis, DeSimone, Joseph, Lavelle, Donald
Publicado no Exp Hematol (2010)

siDNMT1 Increases γ-globin Expression in Chemical-Inducer-of-Dimerization (CID)-Dependent Mouse βYAC Bone Marrow Cells and in Baboon Erythroid Progenitor Cell Cultures

Por Banzon, Virryan, Ibanez, Vinzon, Vaitkus, Kestis, Ruiz, Maria Armila, Peterson, Kenneth, DeSimone, Joseph, Lavelle, Donald
Publicado no Exp Hematol (2010)

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

Por Ruiz, Maria Armila, Rivers, Angela, Ibanez, Vinzon, Vaitkus, Kestis, Mahmud, Nadim, DeSimone, Joseph, Lavelle, Donald
Publicado no Epigenetics (2015)

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

Por Lavelle, Donald, Vaitkus, Kestutis, Ruiz, Maria Armila, Ibanez, Vinzon, Kouznetsova, Tatiana, Saunthararajah, Yogen, Mahmud, Nadim, DeSimone, Joseph
Publicado em 2012

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons

Por Ibanez, Vinzon, Vaitkus, Kestis, Rivers, Angela, Molokie, Robert, Cui, Shuaiying, Engel, James Douglas, DeSimone, Joseph, Lavelle, Donald
Publicado no Blood (2017)

RUNX1 regulates corepressor interactions of PU.1

Por Hu, Zhenbo, Gu, Xiaorong, Baraoidan, Kristine, Ibanez, Vinzon, Sharma, Arun, Kadkol, ShriHari, Munker, Reinhold, Ackerman, Steven, Nucifora, Giuseppina, Saunthararajah, Yogen
Publicado em 2011

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis)

Por Rivers, Angela, Vaitkus, Kestis, Ibanez, Vinzon, Ruiz, Maria Armila, Jagadeeswaran, Ramasamy, Saunthararajah, Yogen, Cui, Shuaiying, Engel, James D., DeSimone, Joseph, Lavelle, Donald
Publicado no Haematologica (2016)

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study

Por Molokie, Robert, Lavelle, Donald, Gowhari, Michel, Pacini, Michael, Krauz, Lani, Hassan, Johara, Ibanez, Vinzon, Ruiz, Maria A., Ng, Kwok Peng, Woost, Philip, Radivoyevitch, Tomas, Pacelli, Daisy, Fada, Sherry, Rump, Matthew, Hsieh, Matthew, Tisdale, John F., Jacobberger, James, Phelps, Mitch, Engel, James Douglas, Saraf, Santhosh, Hsu, Lewis L., Gordeuk, Victor, DeSimone, Joseph, Saunthararajah, Yogen
Publicado no PLoS Med (2017)