Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction

door Vilches-Flores, Alonso, Franklin, Zara, Hauge-Evans, Astrid C., Liu, Bo, Huang, Guo C., Choudhary, Pratik, Jones, Peter M., Persaud, Shanta J.
Gepubliceerd in BBA Clin (2016)

SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells

door Olaniru, Oladapo E., Cheng, Jordan, Ast, Julia, Arvaniti, Anastasia, Atanes, Patricio, Huang, Guo C., King, Aileen J.F., Jones, Peter M., Broichhagen, Johannes, Hodson, David J., Persaud, Shanta J.
Gepubliceerd in Mol Metab (2021)

Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells

door Kronenberg, Deborah, Knight, Robin R., Estorninho, Megan, Ellis, Richard J., Kester, Michel G., de Ru, Arnoud, Eichmann, Martin, Huang, Guo C., Powrie, Jake, Dayan, Colin M., Skowera, Ania, van Veelen, Peter A., Peakman, Mark
Gepubliceerd in 2012

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

door Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Gepubliceerd in Diabetologia (2019)

Structural basis of human β-cell killing by CD8(+) T cells in Type 1 diabetes

door Bulek, Anna M., Cole, David K., Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J., Gostick, Emma, Price, David A., Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J., Sewell, Andrew K.
Gepubliceerd in 2012