Synthesis, Properties and Applications of Diazotrifluropropanoyl-Containing Photoactive Analogues of Farnesyl Diphosphate Containing Modified Linkages for Enhanced Stability

by Hovlid, Marisa L., Edelstein, Rebecca L., Henry, Olivier, Ochocki, Joshua, DeGraw, Amanda, Lenevich, Stepan, Talbot, Trista, Young, Victor G., Hruza, Alan W., Lopez-Gallego, Fernando, Labello, Nicholas P., Strickland, Corey L., Schmidt-Dannert, Claudia, Distefano, Mark D.
Published 2010

Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen

by Bukhtiyarova, Marina, Cook, Erica M., Hancock, Paula J., Hruza, Alan W., Shaw, Anthony W., Adam, Gregory C., Barnard, Richard J. O., McKenna, Philip M., Holloway, M. Katharine, Bell, Ian M., Carroll, Steve, Cornella-Taracido, Ivan, Cox, Christopher D., Kutchukian, Peter S., Powell, David A., Strickland, Corey, Trotter, B. Wesley, Tudor, Matthew, Wolkenberg, Scott, Li, Jing, Tellers, David M.
Published in ACS Med Chem Lett (2020)

MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology

by Boga, Sobhana Babu, Deng, Yongqi, Zhu, Liang, Nan, Yang, Cooper, Alan B., Shipps, Gerald W., Doll, Ronald, Shih, Neng-Yang, Zhu, Hugh, Sun, Robert, Wang, Tong, Paliwal, Sunil, Tsui, Hon-Chung, Gao, Xiaolei, Yao, Xin, Desai, Jagdish, Wang, James, Alhassan, Abdul Basit, Kelly, Joseph, Patel, Mehul, Muppalla, Kiran, Gudipati, Subrahmanyam, Zhang, Li-Kang, Buevich, Alexei, Hesk, David, Carr, Donna, Dayananth, Priya, Black, Stuart, Mei, Hong, Cox, Kathleen, Sherborne, Bradley, Hruza, Alan W., Xiao, Li, Jin, Weihong, Long, Brian, Liu, Gongjie, Taylor, Stacey A., Kirschmeier, Paul, Windsor, William T., Bishop, Robert, Samatar, Ahmed A.
Published in ACS Med Chem Lett (2018)