Assessing barriers to a rational chemoprevention trial design in young patients with familial adenomatous polyposis

Por Wood, Joanna P., Howells, Lynne M., Brown, Karen, Thomas, Anne L.
Publicado no Eur J Cancer Prev (2017)

Effects of Omegaven®, EPA, DHA and oxaliplatin on oesophageal adenocarcinoma cell lines growth, cytokine and cell signal biomarkers expression

Por Eltweri, Amar M., Howells, Lynne M., Thomas, Anne L., Dennison, Ashley R., Bowrey, David J.
Publicado no Lipids Health Dis (2018)

Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line

Por Gescher Andreas, Gallacher-Horley Barbara, Fox Louise H, Howells Lynne M, Hudson E Ann, Manson Margaret M
Publicado em 2003-01-01

Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line

Por Hudson, E Ann, Howells, Lynne M, Gallacher-Horley, Barbara, Fox, Louise H, Gescher, Andreas, Manson, Margaret M
Publicado em 2003

Combining curcumin (C3-complex, Sabinsa) with standard care FOLFOX chemotherapy in patients with inoperable colorectal cancer (CUFOX): study protocol for a randomised control trial

Por Irving, Glen RB, Iwuji, Chinenye OO, Morgan, Bruno, Berry, David P, Steward, William P, Thomas, Anne, Brown, Karen, Howells, Lynne M
Publicado no Trials (2015)

Preclinical Colorectal Cancer Chemopreventive Efficacy and p53-Modulating Activity of 3′,4′,5′-Trimethoxyflavonol, a Quercetin Analog

Por Howells, Lynne M, Britton, Robert G, Mazzoletti, Marco, Greaves, Peter, Broggini, Massimo, Brown, Karen, Steward, William P, Gescher, Andreas J, Sale, Stewart
Publicado em 2010

Characterization and Propagation of Tumor Initiating Cells Derived from Colorectal Liver Metastases: Trials, Tribulations and a Cautionary Note

Por James, Mark I., Howells, Lynne M., Karmokar, Ankur, Higgins, Jennifer A., Greaves, Peter, Cai, Hong, Dennison, Ashley, Metcalfe, Matthew, Garcea, Giuseppe, Lloyd, David M., Berry, David P., Steward, William P., Brown, Karen
Publicado no PLoS One (2015)

Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration - a clinical pilot study including assessment of patient acceptability

Por Irving, Glen R.B., Howells, Lynne M., Sale, Stewart, Kralj-Hans, Ines, Atkin, Wendy S., Clark, Susan K., Britton, Robert G., Jones, Donald J.L, Scott, Edwina N., Berry, David P., Hemingway, David, Miller, Andrew S., Brown, Karen, Gescher, Andreas J., Steward, William P.
Publicado em 2012

Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy

Por James, Mark I., Iwuji, Chinenye, Irving, Glen, Karmokar, Ankur, Higgins, Jennifer A., Griffin-Teal, Nicola, Thomas, Anne, Greaves, Peter, Cai, Hong, Patel, Samita R., Morgan, Bruno, Dennison, Ashley, Metcalfe, Matthew, Garcea, Giuseppe, Lloyd, David M., Berry, David P., Steward, William P., Howells, Lynne M., Brown, Karen
Publicado no Cancer Lett (2015)

Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

Por Myint, Ni Ni Moe, Verma, Ajay M., Fernandez-Garcia, Daniel, Sarmah, Panchali, Tarpey, Patrick S., Al-Aqbi, Saif Sattar, Cai, Hong, Trigg, Ricky, West, Kevin, Howells, Lynne M., Thomas, Anne, Brown, Karen, Guttery, David S., Singh, Baljit, Pringle, Howard J., McDermott, Ultan, Shaw, Jacqui A., Rufini, Alessandro
Publicado no Cell Death Dis (2018)