General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

por Houghten, R A
Publicado 1985

RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model.

por Cadroy, Y, Houghten, R A, Hanson, S R
Publicado 1989

Synthetic combinatorial libraries: novel discovery strategy for identification of antimicrobial agents.

por Blondelle, S E, Pérez-Payá, E, Houghten, R A
Publicado 1996

Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic decapeptide library composed of four trillion (4 x 10(12) sequences.

por Pinilla, C, Appel, J R, Houghten, R A
Publicado 1994

Determination of the secondary structure of selected melittin analogues with different haemolytic activities.

por Pérez-Payá, E, Houghten, R A, Blondelle, S E
Publicado 1994

Mucosal antitoxin response in volunteers to immunization with a synthetic peptide of Escherichia coli heat-stable enterotoxin.

por Klipstein, F A, Engert, R F, Houghten, R A
Publicado 1985

Properties of cross-linked toxoid vaccines made with hyperantigenic forms of synthetic Escherichia coli heat-stable toxin.

por Klipstein, F A, Engert, R F, Houghten, R A
Publicado 1984

Immunological properties of purified Klebsiella pneumoniae heat-stable enterotoxin.

por Klipstein, F A, Engert, R F, Houghten, R A
Publicado 1983

Properties of synthetically produced Escherichia coli heat-stable enterotoxin.

por Klipstein, F A, Engert, R F, Houghten, R A
Publicado 1983

Protection in rabbits immunized with a vaccine of Escherichia coli heat-stable toxin cross-linked to the heat-labile toxin B subunit.

por Klipstein, F A, Engert, R F, Houghten, R A
Publicado 1983

beta-Endorphin: stability, clearance behavior, and entry into the central nervous system after intravenous injection of the tritiated peptide in rats and rabbits.

por Houghten, R A, Swann, R W, Li, C H
Publicado 1980

Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.

por Ruggeri, Z M, Houghten, R A, Russell, S R, Zimmerman, T S
Publicado 1986

A chemically synthesized peptide which elicits humoral and cellular immune responses to mycobacterial antigens.

por Minden, P, Houghten, R A, Spear, J R, Shinnick, T M
Publicado 1986

Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1.

por Hubenthal-Voss, J, Houghten, R A, Pereira, L, Roizman, B
Publicado 1988

Identification of antimicrobial peptides by using combinatorial libraries made up of unnatural amino acids.

por Blondelle, S E, Takahashi, E, Weber, P A, Houghten, R A
Publicado 1994

Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries.

por Blondelle, S E, Takahashi, E, Houghten, R A, Pérez-Payá, E
Publicado 1996

Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries.

por Dooley, C T, Chung, N N, Schiller, P W, Houghten, R A
Publicado 1993

Enzyme-linked immunosorbent assay for Escherichia coli heat-stable enterotoxin.

por Klipstein, F A, Engert, R F, Houghten, R A, Rowe, B
Publicado 1984

Induced conformational states of amphipathic peptides in aqueous/lipid environments.

por Blondelle, S E, Ostresh, J M, Houghten, R A, Pérez-Payá, E
Publicado 1995

Generation of rabbit antipeptide antibodies to HLA-class II antigens by the use of synthetic peptides.

por Chersi, A, Morganti, M C, Chillemi, F, Houghten, R, Cenciarelli, C
Publicado 1988