Imidazolopiperazines: Lead Optimization of the Second-Generation Antimalarial Agents

Por Nagle, Advait, Wu, Tao, Kuhen, Kelli, Gagaring, Kerstin, Borboa, Rachel, Francek, Caroline, Chen, Zhong, Plouffe, David, Lin, Xuena, Caldwell, Christopher, Ek, Jared, Skolnik, Suzanne, Liu, Fenghua, Wang, Jianling, Chang, Jonathan, Li, Chun, Liu, Bo, Hollenbeck, Thomas, Tuntland, Tove, Isbell, John, Chuan, Tiffany, Alper, Philip B., Fischli, Christoph, Brun, Reto, Lakshminarayana, Suresh B., Rottmann, Matthias, Diagana, Thierry T., Winzeler, Elizabeth A., Glynne, Richard, Tully, David C., Chatterjee, Arnab K.
Publicado em 2012

Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases

Por He, Xiaohui, Da Ros, Sara, Nelson, John, Zhu, Xuefeng, Jiang, Tao, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Iskandar, Maya, Espinola, Sheryll, Jia, Yong, Bursulaya, Badry, Kreusch, Andreas, Gao, Mu-Yun, Spraggon, Glen, Baaten, Janine, Clemmer, Leah, Meeusen, Shelly, Huang, David, Hill, Robert, Nguyen-Tran, Vân, Fathman, John, Liu, Bo, Tuntland, Tove, Gordon, Perry, Hollenbeck, Thomas, Ng, Kenneth, Shi, Jian, Bordone, Laura, Liu, Hong
Publicado no ACS Med Chem Lett (2017)

Lead Optimization of Imidazopyrazines: A New Class of Antimalarial with Activity on Plasmodium Liver Stages

Por Zou, Bin, Nagle, Advait, Chatterjee, Arnab K., Leong, Seh Yong, Tan, Liying Jocelyn, Sim, Wei Lin Sandra, Mishra, Pranab, Guntapalli, Prasuna, Tully, David C., Lakshminarayana, Suresh B., Lim, Chek Shik, Tan, Yong Cheng, Abas, Siti Nurdiana, Bodenreider, Christophe, Kuhen, Kelli L., Gagaring, Kerstin, Borboa, Rachel, Chang, Jonathan, Li, Chun, Hollenbeck, Thomas, Tuntland, Tove, Zeeman, Anne-Marie, Kocken, Clemens H. M., McNamara, Case, Kato, Nobutaka, Winzeler, Elizabeth A., Yeung, Bryan K. S., Diagana, Thierry T., Smith, Paul W., Roland, Jason
Publicado em 2014