DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

door Duchon, Arnaud, Herault, Yann
Gepubliceerd in Front Behav Neurosci (2016)

Modeling human disease in rodents by CRISPR/Cas9 genome editing

door Birling, Marie-Christine, Herault, Yann, Pavlovic, Guillaume
Gepubliceerd in Mamm Genome (2017)

Modeling Chromosomes in Mouse to Explore the Function of Genes, Genomic Disorders, and Chromosomal Organization

door Brault, Véronique, Pereira, Patricia, Duchon, Arnaud, Hérault, Yann
Gepubliceerd in 2006

Fork Stalling and Template Switching As a Mechanism for Polyalanine Tract Expansion Affecting the DYC Mutant of HOXD13, a New Murine Model of Synpolydactyly

door Cocquempot, Olivier, Brault, Véronique, Babinet, Charles, Herault, Yann
Gepubliceerd in 2009

RNA-Dependent DNA Binding Activity of the Pur Factor, Potentially Involved in DNA Replication and Gene Transcription

door Herault, Yann, Chatelain, Gilles, Brun, Gilbert, Michel, Denis
Gepubliceerd in Gene Expr (2018)

Dosage of the Abcg1-U2af1 Region Modifies Locomotor and Cognitive Deficits Observed in the Tc1 Mouse Model of Down Syndrome

door Marechal, Damien, Pereira, Patricia Lopes, Duchon, Arnaud, Herault, Yann
Gepubliceerd in PLoS One (2015)

Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

door Teboul, Lydia, Herault, Yann, Wells, Sara, Qasim, Waseem, Pavlovic, Guillaume
Gepubliceerd in Mol Ther (2020)

Introduction to Mammalian Genome Special Issue: Epigenetics

door Beckers, Johannes, Teperino, Raffaele, Hérault, Yann, Hrabé de Angelis, Martin
Gepubliceerd in Mamm Genome (2020)

Inducing Segmental Aneuploid Mosaicism in the Mouse Through Targeted Asymmetric Sister Chromatid Event of Recombination

door Duchon, Arnaud, Besson, Vanessa, Pereira, Patricia Lopes, Magnol, Laetitia, Hérault, Yann
Gepubliceerd in 2008

Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB

door Brault, Véronique, Martin, Benoît, Costet, Nathalie, Bizot, Jean-Charles, Hérault, Yann
Gepubliceerd in 2011

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

door Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
Gepubliceerd in Mol Autism (2021)

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

door Duchon, Arnaud, Raveau, Matthieu, Chevalier, Claire, Nalesso, Valérie, Sharp, Andrew J., Herault, Yann
Gepubliceerd in 2011

Down Syndrome: From Understanding the Neurobiology to Therapy

door Gardiner, Katheleen, Herault, Yann, Lott, Ira T., Antonarakis, Stylianos E., Reeves, Roger H., Dierssen, Mara
Gepubliceerd in 2010

Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media

door Bhutta, Mahmood F., Cheeseman, Michael T., Herault, Yann, Yu, Yuejin E., Brown, Steve D. M.
Gepubliceerd in 2013

Controlled Somatic and Germline Copy Number Variation in the Mouse Model

door Hérault, Yann, Duchon, Arnaud, Maréchal, Damien, Raveau, Matthieu, Pereira, Patricia L., Dalloneau, Emilie, Brault, Véronique
Gepubliceerd in 2010

Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

door Mark, Manuel, Teletin, Marius, Wendling, Olivia, Vonesch, Jean-Luc, Féret, Betty, Hérault, Yann, Ghyselinck, Norbert B.
Gepubliceerd in Biomedicines (2021)

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance

door Rachdi, Latif, Kariyawasam, Dulanjalee, Aïello, Virginie, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël
Gepubliceerd in 2014

Rodent models in Down syndrome research: impact and future opportunities

door Herault, Yann, Delabar, Jean M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Yu, Eugene, Brault, Veronique
Gepubliceerd in Dis Model Mech (2017)

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy

door clar, julie, Gri, Blandine, Calderaro, Julien, Birling, Marie-Christine, Herault, Yann, Smith, Peter, Mithieux, Gilles, Rajas, Fabienne
Gepubliceerd in Kidney Int (2014)

Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus

door Iacono, Giovanni, Benevento, Marco, Dubos, Aline, Herault, Yann, van Bokhoven, Hans, Nadif Kasri, Nael, Stunnenberg, Hendrik G.
Gepubliceerd in Sci Rep (2017)