DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

por Duchon, Arnaud, Herault, Yann
Publicado en Front Behav Neurosci (2016)

Modeling human disease in rodents by CRISPR/Cas9 genome editing

por Birling, Marie-Christine, Herault, Yann, Pavlovic, Guillaume
Publicado en Mamm Genome (2017)

Modeling Chromosomes in Mouse to Explore the Function of Genes, Genomic Disorders, and Chromosomal Organization

por Brault, Véronique, Pereira, Patricia, Duchon, Arnaud, Hérault, Yann
Publicado 2006

Fork Stalling and Template Switching As a Mechanism for Polyalanine Tract Expansion Affecting the DYC Mutant of HOXD13, a New Murine Model of Synpolydactyly

por Cocquempot, Olivier, Brault, Véronique, Babinet, Charles, Herault, Yann
Publicado 2009

RNA-Dependent DNA Binding Activity of the Pur Factor, Potentially Involved in DNA Replication and Gene Transcription

por Herault, Yann, Chatelain, Gilles, Brun, Gilbert, Michel, Denis
Publicado en Gene Expr (2018)

Dosage of the Abcg1-U2af1 Region Modifies Locomotor and Cognitive Deficits Observed in the Tc1 Mouse Model of Down Syndrome

por Marechal, Damien, Pereira, Patricia Lopes, Duchon, Arnaud, Herault, Yann
Publicado en PLoS One (2015)

Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

por Teboul, Lydia, Herault, Yann, Wells, Sara, Qasim, Waseem, Pavlovic, Guillaume
Publicado en Mol Ther (2020)

Introduction to Mammalian Genome Special Issue: Epigenetics

por Beckers, Johannes, Teperino, Raffaele, Hérault, Yann, Hrabé de Angelis, Martin
Publicado en Mamm Genome (2020)

Inducing Segmental Aneuploid Mosaicism in the Mouse Through Targeted Asymmetric Sister Chromatid Event of Recombination

por Duchon, Arnaud, Besson, Vanessa, Pereira, Patricia Lopes, Magnol, Laetitia, Hérault, Yann
Publicado 2008

Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB

por Brault, Véronique, Martin, Benoît, Costet, Nathalie, Bizot, Jean-Charles, Hérault, Yann
Publicado 2011

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

por Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
Publicado en Mol Autism (2021)

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

por Duchon, Arnaud, Raveau, Matthieu, Chevalier, Claire, Nalesso, Valérie, Sharp, Andrew J., Herault, Yann
Publicado 2011

Down Syndrome: From Understanding the Neurobiology to Therapy

por Gardiner, Katheleen, Herault, Yann, Lott, Ira T., Antonarakis, Stylianos E., Reeves, Roger H., Dierssen, Mara
Publicado 2010

Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media

por Bhutta, Mahmood F., Cheeseman, Michael T., Herault, Yann, Yu, Yuejin E., Brown, Steve D. M.
Publicado 2013

Controlled Somatic and Germline Copy Number Variation in the Mouse Model

por Hérault, Yann, Duchon, Arnaud, Maréchal, Damien, Raveau, Matthieu, Pereira, Patricia L., Dalloneau, Emilie, Brault, Véronique
Publicado 2010

Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

por Mark, Manuel, Teletin, Marius, Wendling, Olivia, Vonesch, Jean-Luc, Féret, Betty, Hérault, Yann, Ghyselinck, Norbert B.
Publicado en Biomedicines (2021)

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance

por Rachdi, Latif, Kariyawasam, Dulanjalee, Aïello, Virginie, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël
Publicado 2014

Rodent models in Down syndrome research: impact and future opportunities

por Herault, Yann, Delabar, Jean M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Yu, Eugene, Brault, Veronique
Publicado en Dis Model Mech (2017)

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy

por clar, julie, Gri, Blandine, Calderaro, Julien, Birling, Marie-Christine, Herault, Yann, Smith, Peter, Mithieux, Gilles, Rajas, Fabienne
Publicado en Kidney Int (2014)

Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus

por Iacono, Giovanni, Benevento, Marco, Dubos, Aline, Herault, Yann, van Bokhoven, Hans, Nadif Kasri, Nael, Stunnenberg, Hendrik G.
Publicado en Sci Rep (2017)