Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate

af Cramer-Morales, Kimberly L., Heer, Collin D., Mapuskar, Kranti A., Domann, Frederick E.
Udgivet i J Exp Pathol (Wilmington) (2020)

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

af Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Udgivet i bioRxiv (2020)

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

af Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Udgivet i J Biol Chem (2021)

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD(+)

af Roboon, Jureepon, Hattori, Tsuyoshi, Ishii, Hiroshi, Takarada-Iemata, Mika, Nguyen, Dinh Thi, Heer, Collin D., O’Meally, Denis, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro, Hori, Osamu
Udgivet i J Neurochem (2021)

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H(2)O(2)-Dependent Manner

af Heer, Collin D., Davis, Andrew B., Riffe, David B., Wagner, Brett A., Falls, Kelly C., Allen, Bryan G., Buettner, Garry R., Beardsley, Robert A., Riley, Dennis P., Spitz, Douglas R.
Udgivet i Antioxidants (Basel) (2018)

Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide

af Sishc, Brock J., Ding, Lianghao, Nam, Taek-Keun, Heer, Collin D., Rodman, Samuel N., Schoenfeld, Joshua D., Fath, Melissa A., Saha, Debabrata, Pulliam, Casey F., Langen, Britta, Beardsley, Robert A., Riley, Dennis P., Keene, Jeffery L., Spitz, Douglas R., Story, Michael D.
Udgivet i Sci Transl Med (2021)