Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate

per Cramer-Morales, Kimberly L., Heer, Collin D., Mapuskar, Kranti A., Domann, Frederick E.
Publicat a J Exp Pathol (Wilmington) (2020)

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

per Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Publicat a bioRxiv (2020)

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

per Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Publicat a J Biol Chem (2021)

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD(+)

per Roboon, Jureepon, Hattori, Tsuyoshi, Ishii, Hiroshi, Takarada-Iemata, Mika, Nguyen, Dinh Thi, Heer, Collin D., O’Meally, Denis, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro, Hori, Osamu
Publicat a J Neurochem (2021)

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H(2)O(2)-Dependent Manner

per Heer, Collin D., Davis, Andrew B., Riffe, David B., Wagner, Brett A., Falls, Kelly C., Allen, Bryan G., Buettner, Garry R., Beardsley, Robert A., Riley, Dennis P., Spitz, Douglas R.
Publicat a Antioxidants (Basel) (2018)

Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide

per Sishc, Brock J., Ding, Lianghao, Nam, Taek-Keun, Heer, Collin D., Rodman, Samuel N., Schoenfeld, Joshua D., Fath, Melissa A., Saha, Debabrata, Pulliam, Casey F., Langen, Britta, Beardsley, Robert A., Riley, Dennis P., Keene, Jeffery L., Spitz, Douglas R., Story, Michael D.
Publicat a Sci Transl Med (2021)