The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

par Bamberg, Krister, William-Olsson, Lena, Johansson, Ulrika, Jansson-Löfmark, Rasmus, Hartleib-Geschwindner, Judith
Publié dans J Renin Angiotensin Aldosterone Syst (2019)

Electrolyte handling in the isolated perfused rat kidney: demonstration of vasopressin V2-receptor-dependent calcium reabsorption

par Bamberg, Krister, William-Olsson, Lena, Johansson, Ulrika, Arner, Anders, Hartleib-Geschwindner, Judith, Sällström, Johan
Publié dans Ups J Med Sci (2020)

Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator

par Erlandsson, Fredrik, Albayaty, Muna, Chialda, Ligia, Ericsson, Hans, Amilon, Carl, Nelander, Karin, Jansson‐Löfmark, Rasmus, Wernevik, Linda, Kjaer, Magnus, Bamberg, Krister, Hartleib‐Geschwindner, Judith
Publié dans Br J Clin Pharmacol (2018)

Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study

par Whittaker, Andrew, Kragh, Åsa M., Hartleib‐Geschwindner, Judith, Albayaty, Muna, Backlund, Anna, Greasley, Peter J., Heijer, Maria, Kjaer, Magnus, Forte, Pablo, Unwin, Robert, Wernevik, Linda, Ericsson, Hans
Publié dans Clin Transl Sci (2019)

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

par Bamberg, Krister, Johansson, Ulrika, Edman, Karl, William-Olsson, Lena, Myhre, Susanna, Gunnarsson, Anders, Geschwindner, Stefan, Aagaard, Anna, Björnson Granqvist, Anna, Jaisser, Frédéric, Huang, Yufeng, Granberg, Kenneth L., Jansson-Löfmark, Rasmus, Hartleib-Geschwindner, Judith
Publié dans PLoS One (2018)