A High-throughput Assay for mRNA Silencing in Primary Cortical Neurons in vitro with Oligonucleotide Therapeutics

per Alterman, Julia F., Coles, Andrew H., Hall, Lauren M., Aronin, Neil, Khvorova, Anastasia, Didiot, Marie-Cécile
Publicat a Bio Protoc (2017)

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

per Nikan, Mehran, Osborn, Maire F, Coles, Andrew H, Godinho, Bruno MDC, Hall, Lauren M, Haraszti, Reka A, Hassler, Matthew R, Echeverria, Dimas, Aronin, Neil, Khvorova, Anastasia
Publicat a Mol Ther Nucleic Acids (2016)

Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain

per Alterman, Julia F, Hall, Lauren M, Coles, Andrew H, Hassler, Matthew R, Didiot, Marie-Cecile, Chase, Kathryn, Abraham, Jasmin, Sottosanti, Emily, Johnson, Emily, Sapp, Ellen, Osborn, Maire F, Difiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a Mol Ther Nucleic Acids (2015)

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

per Didiot, Marie-Cécile, Hall, Lauren M, Coles, Andrew H, Haraszti, Reka A, Godinho, Bruno MDC, Chase, Kathryn, Sapp, Ellen, Ly, Socheata, Alterman, Julia F, Hassler, Matthew R, Echeverria, Dimas, Raj, Lakshmi, Morrissey, David V, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a Mol Ther (2016)

Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin

per Didiot, Marie-Cécile, Ferguson, Chantal M., Ly, Socheata, Coles, Andrew H., Smith, Abigail O., Bicknell, Alicia A., Hall, Lauren M., Sapp, Ellen, Echeverria, Dimas, Pai, Athma A., DiFiglia, Marian, Moore, Melissa J., Hayward, Lawrence J., Aronin, Neil, Khvorova, Anastasia
Publicat a Cell Rep (2018)