Binding Kinetics of Darunavir to Human Immunodeficiency Virus Type 1 Protease Explain the Potent Antiviral Activity and High Genetic Barrier

Autor Dierynck, Inge, De Wit, Mieke, Gustin, Emmanuel, Keuleers, Inge, Vandersmissen, Johan, Hallenberger, Sabine, Hertogs, Kurt
Vydáno 2007

Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids

Autor Barbier, Michaël, Jaensch, Steffen, Cornelissen, Frans, Vidic, Suzana, Gjerde, Kjersti, de Hoogt, Ronald, Graeser, Ralph, Gustin, Emmanuel, Chong, Yolanda T.
Vydáno v PLoS One (2016)

Repurposing high-throughput image assays enables biological activity prediction for drug discovery

Autor Simm, Jaak, Klambauer, Günter, Arany, Adam, Steijaert, Marvin, Wegner, Jörg Kurt, Gustin, Emmanuel, Chupakhin, Vladimir, Chong, Yolanda T., Vialard, Jorge, Buijnsters, Peter, Velter, Ingrid, Vapirev, Alexander, Singh, Shantanu, Carpenter, Anne E., Wuyts, Roel, Hochreiter, Sepp, Moreau, Yves, Ceulemans, Hugo
Vydáno v Cell Chem Biol (2018)

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines

Autor Cox, Michael J., Jaensch, Steffen, Van de Waeter, Jelle, Cougnaud, Laure, Seynaeve, Daan, Benalla, Soulaiman, Koo, Seong Joo, Van Den Wyngaert, Ilse, Neefs, Jean-Marc, Malkov, Dmitry, Bittremieux, Mart, Steemans, Margino, Peeters, Pieter J., Wegner, Jörg Kurt, Ceulemans, Hugo, Gustin, Emmanuel, Chong, Yolanda T., Göhlmann, Hinrich W. H.
Vydáno v Sci Rep (2020)