Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine

Por Luo, Guanglin, Chen, Ling, Conway, Charles M., Denton, Rex, Keavy, Deborah, Gulianello, Michael, Huang, Yanling, Kostich, Walter, Lentz, Kimberley A., Mercer, Stephen E., Schartman, Richard, Signor, Laura, Browning, Marc, Macor, John E., Dubowchik, Gene M.
Publicado em 2012

Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators

Por Hill, Matthew D., Fang, Haiquan, Brown, Jeffrey M., Molski, Thaddeus, Easton, Amy, Han, Xiaojun, Miller, Regina, Hill-Drzewi, Melissa, Gallagher, Lizbeth, Matchett, Michele, Gulianello, Michael, Balakrishnan, Anand, Bertekap, Robert L., Santone, Kenneth S., Whiterock, Valerie J., Zhuo, Xiaoliang, Bronson, Joanne J., Macor, John E., Degnan, Andrew P.
Publicado no ACS Med Chem Lett (2016)

Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5

Por Yang, Fukang, Snyder, Lawrence B., Balakrishnan, Anand, Brown, Jeffrey M., Sivarao, Digavalli V., Easton, Amy, Fernandes, Alda, Gulianello, Michael, Hanumegowda, Umesh M., Huang, Hong, Huang, Yanling, Jones, Kelli M., Li, Yu-Wen, Matchett, Michele, Mattson, Gail, Miller, Regina, Santone, Kenneth S., Senapati, Arun, Shields, Eric E., Simutis, Frank J., Westphal, Ryan, Whiterock, Valerie J., Bronson, Joanne J., Macor, John E., Degnan, Andrew P.
Publicado no ACS Med Chem Lett (2016)

Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain

Por Kostich, Walter, Hamman, Brian D., Li, Yu-Wen, Naidu, Sreenivasulu, Dandapani, Kumaran, Feng, Jianlin, Easton, Amy, Bourin, Clotilde, Baker, Kevin, Allen, Jason, Savelieva, Katerina, Louis, Justin V., Dokania, Manoj, Elavazhagan, Saravanan, Vattikundala, Pradeep, Sharma, Vivek, Das, Manish Lal, Shankar, Ganesh, Kumar, Anoop, Holenarsipur, Vinay K., Gulianello, Michael, Molski, Ted, Brown, Jeffrey M., Lewis, Martin, Huang, Yanling, Lu, Yifeng, Pieschl, Rick, O’Malley, Kevin, Lippy, Jonathan, Nouraldeen, Amr, Lanthorn, Thomas H., Ye, Guilan, Wilson, Alan, Balakrishnan, Anand, Denton, Rex, Grace, James E., Lentz, Kimberley A., Santone, Kenneth S., Bi, Yingzhi, Main, Alan, Swaffield, Jon, Carson, Ken, Mandlekar, Sandhya, Vikramadithyan, Reeba K., Nara, Susheel J., Dzierba, Carolyn, Bronson, Joanne, Macor, John E., Zaczek, Robert, Westphal, Ryan, Kiss, Laszlo, Bristow, Linda, Conway, Charles M., Zambrowicz, Brian, Albright, Charles F.
Publicado no J Pharmacol Exp Ther (2016)