MACROPHAGE ACTIVATION SYNDROME AND CYTOKINE DIRECTED THERAPIES

le Schulert, Grant S., Grom, Alexei A.
Foilsithe 2014

Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine-Directed Therapies

le Schulert, Grant S., Grom, Alexei A.
Foilsithe in Annu Rev Med (2014)

Update on the pathogenesis and treatment of systemic idiopathic arthritis

le Sikora, Keith A., Grom, Alexei A.
Foilsithe 2011

Macrophage activation syndrome: advances towards understanding pathogenesis

le Grom, Alexei A., Mellins, Elizabeth D.
Foilsithe in Curr Opin Rheumatol (2010)

Systemic JIA: New Developments in the Understanding of the Pathophysiology and Therapy

le Vastert, Sebastiaan J., Kuis, Wietse, Grom, Alexei A.
Foilsithe 2009

Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

le Mellins, Elizabeth D., Macaubas, Claudia, Grom, Alexei A.
Foilsithe 2011

Macrophage activation syndrome in the era of biologic therapy

le Grom, Alexei A., Horne, AnnaCarin, De Benedetti, Fabrizio
Foilsithe in Nat Rev Rheumatol (2016)

The Limited Role of Interferon-γ in Systemic Juvenile Idiopathic Arthritis Cannot Be Explained by Cellular Hyporesponsiveness

le Sikora, Keith A., Fall, Ndate, Thornton, Sherry, Grom, Alexei A.
Foilsithe 2012

Distinct gene expression signatures characterize strong clinical responders vs non-responders to Canakinumab in children with sJIA

le Verweyen, Emely L, Pickering, Alex, Grom, Alexei A., Schulert, Grant S.
Foilsithe in Arthritis Rheumatol (2021)

MEVALONATE KINASE DEFICIENCY ASSOCIATED WITH RECURRENT LIVER DYSFUNCTION, MACROPHAGE ACTIVATION SYNDROME AND PERFORIN GENE POLYMORPHISM

le Schulert, Grant S., Bove, Kevin, McMasters, Richard, Campbell, Kathleen, Leslie, Nancy, Grom, Alexei A.
Foilsithe in Arthritis Care Res (Hoboken) (2015)

Gene Expression Profiles from Peripheral Blood Mononuclear Cells Are Sensitive to Short Processing Delays

le Barnes, Michael G., Grom, Alexei A., Griffin, Thomas A., Colbert, Robert A., Thompson, Susan D.
Foilsithe 2010

Follistatin-like Protein 1 and the Ferritin/Erythrocyte Sedimentation Rate Ratio Are Potential Biomarkers for Dysregulated Gene Expression and Macrophage Activation Syndrome in Sys...

le Gorelik, Mark, Fall, Ndate, Altaye, Mekibib, Barnes, Michael G., Thompson, Susan D., Grom, Alexei A., Hirsch, Raphael
Foilsithe 2013

Monocyte microRNA expression in active systemic juvenile idiopathic arthritis implicates miR-125a-5p in polarized monocyte phenotypes

le Schulert, Grant S., Fall, Ndate, Harley, John B., Shen, Nan, Lovell, Daniel J., Thornton, Sherry, Grom, Alexei A.
Foilsithe in Arthritis Rheumatol (2016)

Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome

le Villanueva, Joyce, Lee, Susan, Giannini, Edward H, Graham, Thomas B, Passo, Murray H, Filipovich, Alexandra, Grom, Alexei A
Foilsithe 2005

Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis

le Sumegi, Janos, Nestheide, Shawnagay V., Barnes, Michael G., Villanueva, Joyce, Zhang, Kejian, Grom, Alexei A., Filipovich, Alexandra H.
Foilsithe 2013

Novel UNC13D intronic variant disrupting a NFκB enhancer in a patient with recurrent macrophage activation syndrome and systemic juvenile idiopathic arthritis

le Schulert, Grant S., Zhang, Mingce, Husami, Ammar, Fall, Ndate, Brunner, Hermine, Zhang, Kejian, Cron, Randy Q., Grom, Alexei A.
Foilsithe in Arthritis Rheumatol (2018)

A Multi-parameter Flow Cytometry Analysis Panel to Assess CD163 mRNA and Protein in Monocyte and Macrophage Populations in Hyperinflammatory Diseases

le Thornton, Sherry, Tan, Rachel, Sproles, Alyssa, Do, Thuy, Schick, Jonathan, Grom, Alexei A., DeLay, Monica, Schulert, Grant S.
Foilsithe in J Immunol (2019)

Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

le Brown, Rachel A., Henderlight, Maggie, Do, Thuy, Yasin, Shima, Grom, Alexei A., DeLay, Monica, Thornton, Sherry, Schulert, Grant S.
Foilsithe in Front Immunol (2018)

The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis

le Aljaberi, Najla, Tronconi, Elena, Schulert, Grant, Grom, Alexei A., Lovell, Daniel J., Huggins, Jennifer L., Henrickson, Michael, Brunner, Hermine I.
Foilsithe in Pediatr Rheumatol Online J (2020)

Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis

le Barnes, Michael G., Grom, Alexei A., Thompson, Susan D., Griffin, Thomas A., Luyrink, Lorie K., Colbert, Robert A., Glass, David N.
Foilsithe 2010