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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine-Directed Therapies

Macrophage activation syndrome (MAS) is an acute episode of overwhelming inflammation characterized by activation and expansion of T lymphocytes and hemophagocytic macrophages. In rheumatology, it occurs most frequently in patients with systemic juvenile idiopathic arthritis (SJIA) and systemic lupu...

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Bibliografiske detaljer
Udgivet i:Annu Rev Med
Main Authors: Schulert, Grant S., Grom, Alexei A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846123/
https://ncbi.nlm.nih.gov/pubmed/25386930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-061813-012806
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