Model-Based Approach To Characterize Efavirenz Autoinduction and Concurrent Enzyme Induction with Carbamazepine

Autor Zhu, Min, Kaul, Sanjeev, Nandy, Partha, Grasela, Dennis M., Pfister, Marc
Vydáno 2009

Pharmacodynamics of Fluoroquinolones against Streptococcus pneumoniae in Patients with Community-Acquired Respiratory Tract Infections

Autor Ambrose, Paul G., Grasela, Dennis M., Grasela, Thaddeus H., Passarell, Julie, Mayer, Howard B., Pierce, Phillip F.
Vydáno 2001

Safety, pharmacokinetics and pharmacodynamics of branebrutinib (BMS‐986195), a covalent, irreversible inhibitor of Bruton's tyrosine kinase: Randomised phase I, placebo‐controlled...

Autor Catlett, Ian M., Nowak, Miroslawa, Kundu, Sudeep, Zheng, Naiyu, Liu, Ang, He, Bing, Girgis, Ihab G., Grasela, Dennis M.
Vydáno v Br J Clin Pharmacol (2020)

Pharmacokinetics of Single-Dose Oral Stavudine in Subjects with Renal Impairment and in Subjects Requiring Hemodialysis

Autor Grasela, Dennis M., Stoltz, Randall R., Barry, Michael, Bone, Michael, Mangold, Bernhard, O'Grady, Padraig, Raymond, Ralph, Haworth, Stephen J.
Vydáno 2000

Pharmacokinetics of Gatifloxacin in Infants and Children

Autor Capparelli, Edmund V., Reed, Michael D., Bradley, John S., Kearns, Gregory L., Jacobs, Richard F., Damle, Bharat D., Blumer, Jeffrey L., Grasela, Dennis M.
Vydáno 2005

Population Pharmacokinetic Model for Gatifloxacin in Pediatric Patients

Autor Rubino, Christopher M., Capparelli, Edmund V., Bradley, John S., Blumer, Jeffrey L., Kearns, Gregory L., Reed, Michael, Jacobs, Richard F., Cirincione, Brenda, Grasela, Dennis M.
Vydáno 2007

Antiviral Activity, Pharmacokinetics, and Safety of BMS-488043, a Novel Oral Small-Molecule HIV-1 Attachment Inhibitor, in HIV-1-Infected Subjects

Autor Hanna, George J., Lalezari, Jacob, Hellinger, James A., Wohl, David A., Nettles, Richard, Persson, Anna, Krystal, Mark, Lin, Pinfang, Colonno, Richard, Grasela, Dennis M.
Vydáno 2011

Randomized, Placebo-Controlled, Single-Ascending-Dose Study of BMS-791325, a Hepatitis C Virus (HCV) NS5B Polymerase Inhibitor, in HCV Genotype 1 Infection

Autor Sims, Karen D., Lemm, Julie, Eley, Timothy, Liu, Menping, Berglind, Anna, Sherman, Diane, Lawitz, Eric, Vutikullird, Apinya B., Tebas, Pablo, Gao, Min, Pasquinelli, Claudio, Grasela, Dennis M.
Vydáno 2014

Population Pharmacokinetics and Pharmacodynamics of Garenoxacin in Patients with Community-Acquired Respiratory Tract Infections

Autor Van Wart, Scott, Phillips, Luann, Ludwig, Elizabeth A., Russo, Rene, Gajjar, Diptee A., Bello, Akintunde, Ambrose, Paul G., Costanzo, Christopher, Grasela, Thaddeus H., Echols, Roger, Grasela, Dennis M.
Vydáno 2004

Immune checkpoint inhibition in sepsis: a Phase 1b randomized, placebo-controlled, single ascending dose study of anti-PD-L1 (BMS-936559)

Autor Hotchkiss, Richard S., Colston, Elizabeth, Yende, Sachin, Angus, Derek C., Moldawer, Lyle L., Crouser, Elliott D., Martin, Greg S., Coopersmith, Craig M., Brakenridge, Scott, Mayr, Florian B., Park, Pauline K., Ye, June, Catlett, Ian M., Girgis, Ihab G., Grasela, Dennis M.
Vydáno v Crit Care Med (2019)

Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy

Autor Gay, Cynthia L., Bosch, Ronald J, Ritz, Justin, Hataye, Jason M., Aga, Evgenia, Tressler, Randall L., Mason, Stephen W., Hwang, Carey K., Grasela, Dennis M., Ray, Neelanjana, Cyktor, Josh C., Coffin, John M., Acosta, Edward P., Koup, Richard A., Mellors, John W., Eron, Joseph J.
Vydáno v J Infect Dis (2017)

Single- and Multiple-Ascending-Dose Studies of the NS3 Protease Inhibitor Asunaprevir in Subjects with or without Chronic Hepatitis C

Autor Pasquinelli, Claudio, McPhee, Fiona, Eley, Timothy, Villegas, Criselda, Sandy, Katrina, Sheridan, Pamela, Persson, Anna, Huang, Shu-Pang, Hernandez, Dennis, Sheaffer, Amy K., Scola, Paul, Marbury, Thomas, Lawitz, Eric, Goldwater, Ronald, Rodriguez-Torres, Maribel, DeMicco, Michael, Wright, David, Charlton, Michael, Kraft, Walter K., Lopez-Talavera, Juan-Carlos, Grasela, Dennis M.
Vydáno 2012

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

Autor Gao, Min, Nettles, Richard E., Belema, Makonen, Snyder, Lawrence B., Nguyen, Van N., Fridell, Robert A., Serrano-Wu, Michael H., Langley, David R., Sun, Jin-Hua, O’Boyle II, Donald R., Lemm, Julie A., Wang, Chunfu, Knipe, Jay O., Chien, Caly, Colonno, Richard J., Grasela, Dennis M., Meanwell, Nicholas A., Hamann, Lawrence G.
Vydáno v Nature (2010)