Physiologically‐Based Pharmacokinetic Modeling of Remdesivir and Its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients With COVID‐19

Autor Lutz, Justin D., Mathias, Anita, German, Polina, Pikora, Cheryl, Reddy, Sunila, Kirby, Brian J.
Vydáno v Clin Pharmacol Ther (2021)

Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects

Autor Humeniuk, Rita, Mathias, Anita, Cao, Huyen, Osinusi, Anu, Shen, Gong, Chng, Estelle, Ling, John, Vu, Amanda, German, Polina
Vydáno v Clin Transl Sci (2020)

Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clini...

Autor Xiao, Deqing, John Ling, Kah Hiing, Tarnowski, Thomas, Humeniuk, Rita, German, Polina, Mathias, Anita, Chu, Jasper, Chen, Yuan-Shek, van Ingen, Eric
Vydáno v Anal Biochem (2021)

Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects

Autor Mogalian, Erik, German, Polina, Kearney, Brian P., Yang, Cheng Yong, Brainard, Diana, Link, John, McNally, John, Han, LingLing, Ling, John, Mathias, Anita
Vydáno v Antimicrob Agents Chemother (2017)

Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor

Autor Humeniuk, Rita, Mathias, Anita, Kirby, Brian J., Lutz, Justin D., Cao, Huyen, Osinusi, Anu, Babusis, Darius, Porter, Danielle, Wei, Xuelian, Ling, John, Reddy, Y. Sunila, German, Polina
Vydáno v Clin Pharmacokinet (2021)

Pharmacokinetics of Artemether-Lumefantrine and Artesunate-Amodiaquine in Children in Kampala, Uganda

Autor Mwesigwa, Julia, Parikh, Sunil, McGee, Bryan, German, Polina, Drysdale, Troy, Kalyango, Joan N., Clark, Tamara D., Dorsey, Grant, Lindegardh, Niklas, Annerberg, Anna, Rosenthal, Philip J., Kamya, Moses R., Aweeka, Francesca
Vydáno 2010

1002. A Daily Single Tablet Regimen (STR) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Virologically-Suppressed Adults Living with HIV and End Stage Renal Diseas...

Autor Eron, Joseph J, Wilkin, Aimee, Ramgopal, Moti, Osiyemi, Olayemi, McKellar, Mehri, McKellar, Mehri, Slim, Jihad, Asmuth, David, DeJesus, Edwin, German, Polina, Blair, Christiana, Carter, Christoph C, Brainard, Diana M, Collins, Sean E, Martin, Hal
Vydáno v Open Forum Infect Dis (2020)

A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic C...

Autor Marty, Francisco M, Chemaly, Roy F, Mullane, Kathleen M, Lee, Dong-Gun, Hirsch, Hans H, Small, Catherine B, Bergeron, Anne, Shoham, Shmuel, Ljungman, Per, Waghmare, Alpana, Blanchard, Elodie, Kim, Yae-Jean, McKevitt, Matt, Porter, Danielle P, Jordan, Robert, Guo, Ying, German, Polina, Boeckh, Michael, Watkins, Timothy R, Chien, Jason W, Dadwal, Sanjeet S
Vydáno v Clin Infect Dis (2019)

Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1

Autor Naggie, Susanna, Cooper, Curtis, Saag, Michael, Workowski, Kimberly, Ruane, Peter, Towner, William J., Marks, Kristen, Luetkemeyer, Anne, Baden, Rachel P., Sax, Paul E., Gane, Edward, Santana-Bagur, Jorge, Stamm, Luisa M., Yang, Jenny C., German, Polina, Dvory-Sobol, Hadas, Ni, Liyun, Pang, Phillip S., McHutchison, John G., Stedman, Catherine A.M., Morales-Ramirez, Javier O., Bräu, Norbert, Jayaweera, Dushyantha, Colson, Amy E., Tebas, Pablo, Wong, David K., Dieterich, Douglas, Sulkowski, Mark
Vydáno v N Engl J Med (2015)

A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell...

Autor Chemaly, Roy F, Dadwal, Sanjeet S, Bergeron, Anne, Ljungman, Per, Kim, Yae-Jean, Cheng, Guang-Shing, Pipavath, Sudhakar N, Limaye, Ajit P, Blanchard, Elodie, Winston, Drew J, Stiff, Patrick J, Zuckerman, Tsila, Lachance, Silvy, Rahav, Galia, Small, Catherine B, Mullane, Kathleen M, Patron, Roberto L, Lee, Dong-Gun, Hirsch, Hans H, Waghmare, Alpana, McKevitt, Matt, Jordan, Robert, Guo, Ying, German, Polina, Porter, Danielle P, Gossage, David L, Watkins, Timothy R, Marty, Francisco M, Chien, Jason W, Boeckh, Michael
Vydáno v Clin Infect Dis (2019)