Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice

Por Agustín-Pavón, Carmen, Mielcarek, Michal, Garriga-Canut, Mireia, Isalan, Mark
Publicado no Mol Neurodegener (2016)

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice

Por Garriga-Canut, Mireia, Agustín-Pavón, Carmen, Herrmann, Frank, Sánchez, Aurora, Dierssen, Mara, Fillat, Cristina, Isalan, Mark
Publicado em 2012

Evolvability and hierarchy in rewired bacterial gene networks

Por Isalan, Mark, Lemerle, Caroline, Michalodimitrakis, Konstantinos, Beltrao, Pedro, Horn, Carsten, Raineri, Emanuele, Garriga-Canut, Mireia, Serrano, Luis
Publicado em 2008

p53 Gene Repair with Zinc Finger Nucleases Optimised by Yeast 1-Hybrid and Validated by Solexa Sequencing

Por Herrmann, Frank, Garriga-Canut, Mireia, Baumstark, Rebecca, Fajardo-Sanchez, Emmanuel, Cotterell, James, Minoche, André, Himmelbauer, Heinz, Isalan, Mark
Publicado em 2011