Antisense RNA foci are associated with nucleoli and TDP-43 mislocalization in C9orf72-ALS/FTD: A quantitative study

por Arogundade, Olubankole Aladesuyi, Stauffer, Jennifer E., Saberi, Shahram, Garcia, Sandra Diaz, Malik, Sahana, Basilim, Hani, Rodriguez, Maria J, Ohkubo, Takuya, Ravits, John
Publicado en Acta Neuropathol (2019)

Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat expanded C9orf72 amyotrophic lateral scle...

por Saberi, Shahram, Stauffer, Jennifer E., Jiang, Jie, Garcia, Sandra Diaz, Taylor, Amy E, Schulte, Derek, Ohkubo, Takuya, Schloffman, Cheyenne L., Maldonado, Marcus, Baughn, Michael, Rodriguez, Maria J, Pizzo, Don, Cleveland, Don, Ravits, John
Publicado en Acta Neuropathol (2017)

Reduced C9ORF72 function exacerbates gain-of-toxicity from ALS/FTD-causing repeat expansion in C9orf72

por Zhu, Qiang, Jiang, Jie, Gendron, Tania F., McAlonis-Downes, Melissa, Jiang, Lulin, Taylor, Amy, Garcia, Sandra Diaz, Dastidar, Somasish Ghosh, Rodriguez, Maria J., King, Patrick, Zhang, Yongjie, La Spada, Albert R., Xu, Huaxi, Petrucelli, Leonard, Ravits, John, Da Cruz, Sandrine, Lagier-Tourenne, Clotilde, Cleveland, Don W.
Publicado en Nat Neurosci (2020)