An ErbB3 antibody, MM-121, is active in cancers with ligand dependent activation

מאת Schoeberl, Birgit, Faber, Anthony C., Li, Danan, Liang, Mei-Chih, Crosby, Katherine, Onsum, Matthew, Burenkova, Olga, Pace, Emily, Walton, Zandra, Nie, Lin, Fulgham, Aaron, Song, Youngchul, Nielsen, Ulrik B., Engelman, Jeffrey A., Wong, Kwok-Kin
יצא לאור 2010

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

מאת Casaletto, Jessica B., Geddie, Melissa L., Abu-Yousif, Adnan O., Masson, Kristina, Fulgham, Aaron, Boudot, Antoine, Maiwald, Tim, Kearns, Jeffrey D., Kohli, Neeraj, Su, Stephen, Razlog, Maja, Raue, Andreas, Kalra, Ashish, Håkansson, Maria, Logan, Derek T., Welin, Martin, Chattopadhyay, Shrikanta, Harms, Brian D., Nielsen, Ulrik B., Schoeberl, Birgit, Lugovskoy, Alexey A., MacBeath, Gavin
הוצא לאור ב Proc Natl Acad Sci U S A (2019)

Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)

מאת Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
הוצא לאור ב NPJ Syst Biol Appl (2017)