The Effects of Combinatorial Chemistry and Technologies on Drug Discovery and Biotechnology – a Mini Review

por Seneci Pierfausto, Fassina Giorgio, Frecer Vladimir, Miertus Stanislav
Publicado 2014-12-01

Design of Thymidine Analogues Targeting Thymidilate Kinase of Mycobacterium tuberculosis

por Owono Owono, Luc Calvin, Keita, Melalie, Megnassan, Eugene, Frecer, Vladimir, Miertus, Stanislav
Publicado 2013

One step at a time: Action mechanism of Sushi 1 antimicrobial peptide and derived molecules

por Leptihn, Sebastian, Guo, Lin, Frecer, Vladimir, Ho, Bow, Ding, Jeak Ling, Wohland, Thorsten
Publicado 2010

A Novel Human Tectonin Protein with Multivalent β-Propeller Folds Interacts with Ficolin and Binds Bacterial LPS

por Low, Diana Hooi Ping, Ang, Zhiwei, Yuan, Quan, Frecer, Vladimir, Ho, Bow, Chen, Jianzhu, Ding, Jeak Ling
Publicado 2009

Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone–chalcone and isatin–chalcone inhibitors probing the S2 active site pocket

por Allangba, Koffi N’Guessan Placide Gabin, Keita, Mélalie, Kre N’Guessan, Raymond, Megnassan, Eugene, Frecer, Vladimir, Miertus, Stanislav
Publicado en J Enzyme Inhib Med Chem (2019)

Molecular Interfaces of the Galactose-binding Protein Tectonin Domains in Host-Pathogen Interaction

por Low, Diana Hooi Ping, Frecer, Vladimir, Le Saux, Agnès, Srinivasan, Ganesh Anand, Ho, Bow, Chen, Jianzhu, Ding, Jeak Ling
Publicado 2010

Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic...

por Kouassi, Affiba Florance, Kone, Mawa, Keita, Melalie, Esmel, Akori, Megnassan, Eugene, N’Guessan, Yao Thomas, Frecer, Vladimir, Miertus, Stanislav
Publicado en Int J Mol Sci (2015)

Structure-Based Design and in Silico Screening of Virtual Combinatorial Library of Benzamides Inhibiting 2-trans Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis...

por Kouman, Koffi Charles, Keita, Melalie, Kre N’Guessan, Raymond, Owono Owono, Luc Calvin, Megnassan, Eugene, Frecer, Vladimir, Miertus, Stanislav
Publicado en Int J Mol Sci (2019)

Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology

por Frecer, Vladimir, Iarossi, Giancarlo, Salvetti, Anna Paola, Maltese, Paolo Enrico, Delledonne, Giulia, Oldani, Marta, Staurenghi, Giovanni, Falsini, Benedetto, Minnella, Angelo Maria, Ziccardi, Lucia, Magli, Adriano, Colombo, Leonardo, D’Esposito, Fabiana, Miertus, Jan, Viola, Francesco, Attanasio, Marcella, Maggio, Emilia, Bertelli, Matteo
Publicado en J Transl Med (2019)