Epratuzumab inhibits the production of the proinflammatory cytokines IL-6 and TNF-α, but not the regulatory cytokine IL-10, by B cells from healthy donors and SLE patients

Por Fleischer, Vanessa, Sieber, Julia, Fleischer, Sarah J., Shock, Anthony, Heine, Guido, Daridon, Capucine, Dörner, Thomas
Publicado no Arthritis Res Ther (2015)

Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor

Por Lumb, Simon, Fleischer, Sarah J., Wiedemann, Annika, Daridon, Capucine, Maloney, Alison, Shock, Anthony, Dörner, Thomas
Publicado no J Cell Commun Signal (2016)

Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation

Por Sieber, Julia, Daridon, Capucine, Fleischer, Sarah J, Fleischer, Vanessa, Hiepe, Falk, Alexander, Tobias, Heine, Guido, Burmester, Gerd R, Fillatreau, Simon, Dörner, Thomas
Publicado no Arthritis Res Ther (2014)

SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren's syndrome

Por Rose, Thomas, Szelinski, Franziska, Lisney, Anna, Reiter, Karin, Fleischer, Sarah J, Burmester, Gerd R, Radbruch, Andreas, Hiepe, Falk, Grützkau, Andreas, Biesen, Robert, Dörner, Thomas
Publicado no RMD Open (2016)