Autophagy inhibition improves anti-cancer drugs via FOXO3a activation

Yazar: Fitzwalter, Brent E., Thorburn, Andrew
Yayımlandı Oncotarget (2018)

FOXO3 links autophagy to apoptosis

Yazar: Fitzwalter, Brent E., Thorburn, Andrew
Yayımlandı Autophagy (2018)

LGG-37. ASSESSMENT OF EARLY STAGE AUTOPHAGY INHIBITION IN BRAF(V600E) BRAIN TUMOR CELL RESPONSE TO CHEMOTHERAPY

Yazar: Zahedi, Shadi, Fitzwalter, Brent E, Gustafson, Daniel L, Morin, Andrew, Desmarais, Michele, Hoffman, Lindsey M, Levy, Jean M Mulcahy
Yayımlandı Neuro Oncol (2018)

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

Yazar: Towers, Christina G., Fitzwalter, Brent E., Regan, Daniel, Goodspeed, Andrew, Morgan, Michael J., Liu, Chang-Wei, Gustafson, Daniel L., Thorburn, Andrew
Yayımlandı Dev Cell (2019)

Metastatic cells are preferentially vulnerable to lysosomal inhibition

Yazar: Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew
Yayımlandı Proc Natl Acad Sci U S A (2018)

Effect of early-stage autophagy inhibition in BRAF(V600E) autophagy-dependent brain tumor cells

Yazar: Zahedi, Shadi, Fitzwalter, Brent E., Morin, Andrew, Grob, Sydney, Desmarais, Michele, Nellan, Anandani, Green, Adam L., Vibhakar, Rajeev, Hankinson, Todd C., Foreman, Nicholas K., Mulcahy Levy, Jean M.
Yayımlandı Cell Death Dis (2019)

Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover

Yazar: Fitzwalter, Brent E., Towers, Christina G., Sullivan, Kelly D., Andrysik, Zdenek, Hoh, Maria, Ludwig, Michael, O’Prey, Jim, Ryan, Kevin M., Espinosa, Joaquin M., Morgan, Michael J., Thorburn, Andrew
Yayımlandı Dev Cell (2018)

ZZ-dependent regulation of p62/SQSTM1 in autophagy

Yazar: Zhang, Yi, Mun, Su Ran, Linares, Juan F., Ahn, JaeWoo, Towers, Christina G., Ji, Chang Hoon, Fitzwalter, Brent E., Holden, Michael R., Mi, Wenyi, Shi, Xiaobing, Moscat, Jorge, Thorburn, Andrew, Diaz-Meco, Maria T., Kwon, Yong Tae, Kutateladze, Tatiana G.
Yayımlandı Nat Commun (2018)

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

Yazar: Mulcahy Levy, Jean M, Zahedi, Shadi, Griesinger, Andrea M, Morin, Andrew, Davies, Kurtis D, Aisner, Dara L, Kleinschmidt-DeMasters, BK, Fitzwalter, Brent E, Goodall, Megan L, Thorburn, Jacqueline, Amani, Vladimir, Donson, Andrew M, Birks, Diane K, Mirsky, David M, Hankinson, Todd C, Handler, Michael H, Green, Adam L, Vibhakar, Rajeev, Foreman, Nicholas K, Thorburn, Andrew
Yayımlandı eLife (2017)