Autophagy inhibition improves anti-cancer drugs via FOXO3a activation

le Fitzwalter, Brent E., Thorburn, Andrew
Foilsithe in Oncotarget (2018)

FOXO3 links autophagy to apoptosis

le Fitzwalter, Brent E., Thorburn, Andrew
Foilsithe in Autophagy (2018)

LGG-37. ASSESSMENT OF EARLY STAGE AUTOPHAGY INHIBITION IN BRAF(V600E) BRAIN TUMOR CELL RESPONSE TO CHEMOTHERAPY

le Zahedi, Shadi, Fitzwalter, Brent E, Gustafson, Daniel L, Morin, Andrew, Desmarais, Michele, Hoffman, Lindsey M, Levy, Jean M Mulcahy
Foilsithe in Neuro Oncol (2018)

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

le Towers, Christina G., Fitzwalter, Brent E., Regan, Daniel, Goodspeed, Andrew, Morgan, Michael J., Liu, Chang-Wei, Gustafson, Daniel L., Thorburn, Andrew
Foilsithe in Dev Cell (2019)

Metastatic cells are preferentially vulnerable to lysosomal inhibition

le Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew
Foilsithe in Proc Natl Acad Sci U S A (2018)

Effect of early-stage autophagy inhibition in BRAF(V600E) autophagy-dependent brain tumor cells

le Zahedi, Shadi, Fitzwalter, Brent E., Morin, Andrew, Grob, Sydney, Desmarais, Michele, Nellan, Anandani, Green, Adam L., Vibhakar, Rajeev, Hankinson, Todd C., Foreman, Nicholas K., Mulcahy Levy, Jean M.
Foilsithe in Cell Death Dis (2019)

Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover

le Fitzwalter, Brent E., Towers, Christina G., Sullivan, Kelly D., Andrysik, Zdenek, Hoh, Maria, Ludwig, Michael, O’Prey, Jim, Ryan, Kevin M., Espinosa, Joaquin M., Morgan, Michael J., Thorburn, Andrew
Foilsithe in Dev Cell (2018)

ZZ-dependent regulation of p62/SQSTM1 in autophagy

le Zhang, Yi, Mun, Su Ran, Linares, Juan F., Ahn, JaeWoo, Towers, Christina G., Ji, Chang Hoon, Fitzwalter, Brent E., Holden, Michael R., Mi, Wenyi, Shi, Xiaobing, Moscat, Jorge, Thorburn, Andrew, Diaz-Meco, Maria T., Kwon, Yong Tae, Kutateladze, Tatiana G.
Foilsithe in Nat Commun (2018)

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

le Mulcahy Levy, Jean M, Zahedi, Shadi, Griesinger, Andrea M, Morin, Andrew, Davies, Kurtis D, Aisner, Dara L, Kleinschmidt-DeMasters, BK, Fitzwalter, Brent E, Goodall, Megan L, Thorburn, Jacqueline, Amani, Vladimir, Donson, Andrew M, Birks, Diane K, Mirsky, David M, Hankinson, Todd C, Handler, Michael H, Green, Adam L, Vibhakar, Rajeev, Foreman, Nicholas K, Thorburn, Andrew
Foilsithe in eLife (2017)