Autophagy inhibition improves anti-cancer drugs via FOXO3a activation

af Fitzwalter, Brent E., Thorburn, Andrew
Udgivet i Oncotarget (2018)

FOXO3 links autophagy to apoptosis

af Fitzwalter, Brent E., Thorburn, Andrew
Udgivet i Autophagy (2018)

LGG-37. ASSESSMENT OF EARLY STAGE AUTOPHAGY INHIBITION IN BRAF(V600E) BRAIN TUMOR CELL RESPONSE TO CHEMOTHERAPY

af Zahedi, Shadi, Fitzwalter, Brent E, Gustafson, Daniel L, Morin, Andrew, Desmarais, Michele, Hoffman, Lindsey M, Levy, Jean M Mulcahy
Udgivet i Neuro Oncol (2018)

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

af Towers, Christina G., Fitzwalter, Brent E., Regan, Daniel, Goodspeed, Andrew, Morgan, Michael J., Liu, Chang-Wei, Gustafson, Daniel L., Thorburn, Andrew
Udgivet i Dev Cell (2019)

Metastatic cells are preferentially vulnerable to lysosomal inhibition

af Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew
Udgivet i Proc Natl Acad Sci U S A (2018)

Effect of early-stage autophagy inhibition in BRAF(V600E) autophagy-dependent brain tumor cells

af Zahedi, Shadi, Fitzwalter, Brent E., Morin, Andrew, Grob, Sydney, Desmarais, Michele, Nellan, Anandani, Green, Adam L., Vibhakar, Rajeev, Hankinson, Todd C., Foreman, Nicholas K., Mulcahy Levy, Jean M.
Udgivet i Cell Death Dis (2019)

Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover

af Fitzwalter, Brent E., Towers, Christina G., Sullivan, Kelly D., Andrysik, Zdenek, Hoh, Maria, Ludwig, Michael, O’Prey, Jim, Ryan, Kevin M., Espinosa, Joaquin M., Morgan, Michael J., Thorburn, Andrew
Udgivet i Dev Cell (2018)

ZZ-dependent regulation of p62/SQSTM1 in autophagy

af Zhang, Yi, Mun, Su Ran, Linares, Juan F., Ahn, JaeWoo, Towers, Christina G., Ji, Chang Hoon, Fitzwalter, Brent E., Holden, Michael R., Mi, Wenyi, Shi, Xiaobing, Moscat, Jorge, Thorburn, Andrew, Diaz-Meco, Maria T., Kwon, Yong Tae, Kutateladze, Tatiana G.
Udgivet i Nat Commun (2018)

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

af Mulcahy Levy, Jean M, Zahedi, Shadi, Griesinger, Andrea M, Morin, Andrew, Davies, Kurtis D, Aisner, Dara L, Kleinschmidt-DeMasters, BK, Fitzwalter, Brent E, Goodall, Megan L, Thorburn, Jacqueline, Amani, Vladimir, Donson, Andrew M, Birks, Diane K, Mirsky, David M, Hankinson, Todd C, Handler, Michael H, Green, Adam L, Vibhakar, Rajeev, Foreman, Nicholas K, Thorburn, Andrew
Udgivet i eLife (2017)