Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation

por Farand, Julie, Kropf, Jeffrey E., Blomgren, Peter, Xu, Jianjun, Schmitt, Aaron C., Newby, Zachary E., Wang, Ting, Murakami, Eisuke, Barauskas, Ona, Sudhamsu, Jawahar, Feng, Joy Y., Niedziela-Majka, Anita, Schultz, Brian E., Schwartz, Karen, Viatchenko-Karpinski, Serge, Kornyeyev, Dmytro, Kashishian, Adam, Fan, Peidong, Chen, Xiaowu, Lansdon, Eric B., Ports, Michael O., Currie, Kevin S., Watkins, William J., Notte, Gregory T.
Publicado en ACS Med Chem Lett (2019)