Azacyclic FTY720 Analogues that Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill...

Por Chen, Bin, Roy, Saurabh G., McMonigle, Ryan J., Keebaugh, Andrew, McCracken, Alison N., Selwan, Elizabeth, Fransson, Rebecca, Fallegger, Daniel, Huwiler, Andrea, Kleinman, Michael T., Edinger, Aimee L., Hanessian, Stephen
Publicado no ACS Chem Biol (2015)

Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation

Por McCracken, Alison N., McMonigle, Ryan J., Tessier, Jérémie, Fransson, Rebecca, Perryman, Michael S., Chen, Bin, Keebaugh, Andrew, Selwan, Elizabeth, Barr, Sarah A., Kim, Seong M., Roy, Saurabh G., Liu, Gang, Fallegger, Daniel, Sernissi, Lorenzo, Brandt, Cordelia, Moitessier, Nicolas, Snider, Ashley J., Clare, Simon, Müschen, Markus, Huwiler, Andrea, Kleinman, Michael T., Hanessian, Stephen, Edinger, Aimee L.
Publicado no Leukemia (2016)