The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

Por Eckford, Paul D. W., Sharom, Frances J.
Publicado em 2005

The reconstituted Escherichia coli MsbA protein displays lipid flippase activity

Por Eckford, Paul D. W., Sharom, Frances J.
Publicado em 2010

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Por Eckford, Paul D. W., Li, Canhui, Bear, Christine E.
Publicado no J Vis Exp (2015)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiator VX-770 (Ivacaftor) Opens the Defective Channel Gate of Mutant CFTR in a Phosphorylation-dependent but ATP-ind...

Por Eckford, Paul D. W., Li, Canhui, Ramjeesingh, Mohabir, Bear, Christine E.
Publicado em 2012

Functional Rescue of F508del-CFTR Using Small Molecule Correctors

Por Molinski, Steven, Eckford, Paul D. W., Pasyk, Stan, Ahmadi, Saumel, Chin, Stephanie, Bear, Christine E.
Publicado em 2012

Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

Por Islam, Salim T., Eckford, Paul D. W., Jones, Michelle L., Nugent, Timothy, Bear, Christine E., Vogel, Christian, Lam, Joseph S.
Publicado em 2013

Attenuation of Phosphorylation-dependent Activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Disease-causing Mutations at the Transmission Interface

Por Chin, Stephanie, Yang, Donghe, Miles, Andrew J., Eckford, Paul D. W., Molinski, Steven, Wallace, B. A., Bear, Christine E.
Publicado no J Biol Chem (2017)

Synthesis and Properties of Molecular Probes for the Rescue Site on Mutant Cystic Fibrosis Transmembrane Conductance Regulator

Por Alkhouri, Bashar, Denning, Robert A., Kim Chiaw, Patrick, Eckford, Paul D. W., Yu, Wilson, Li, Canhui, Bogojeski, Jovanka J., Bear, Christine E., Viirre, Russell D.
Publicado em 2011

Structural basis for alginate secretion across the bacterial outer membrane

Por Whitney, John C., Hay, Iain D., Li, Canhui, Eckford, Paul D. W., Robinson, Howard, Amaya, Maria F., Wood, Lynn F., Ohman, Dennis E., Bear, Christine E., Rehm, Bernd H., Lynne Howell, P.
Publicado em 2011