A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors

von Smith, David C., Chugh, Rashmi, Patnaik, Amita, Papadopoulos, Kyriakos P., Wang, Min, Kapoun, Ann M., Xu, Lu, Dupont, Jakob, Stagg, Robert J., Tolcher, Anthony
Veröffentlicht in Invest New Drugs (2018)

A phase I study of subcutaneously administered aflibercept (VEGF trap) in a new formulation in patients with advanced solid tumors

von Wang-Gillam, Andrea, Tew, William P., Rothenberg, Mace L., Dupont, Jakob, Cooper, Wendy, Sternas, Lars, Buzenet, Giliane, Sosman, Jeffrey A., Spriggs, David R., Lockhart, Albert Craig
Veröffentlicht 2011

Phase 1 Study of VEGF Trap (Aflibercept) Administered Subcutaneously to Patients with Advanced Solid Tumors

von Tew, William P., Gordon, Michael, Murren, John, Dupont, Jakob, Pezzulli, Sandra, Aghajanian, Carol, Sabbatini, Paul, Mendelson, David, Schwartz, Lawrence, Gettinger, Scott, Psyrri, Amanda, Cedarbaum, Jesse M., Spriggs, David R.
Veröffentlicht 2009

Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas

von Zang, Xingxing, Sullivan, Peggy S, Soslow, Robert A, Waitz, Rebecca, Reuter, Victor E, Wilton, Andrew, Thaler, Howard T, Arul, Manonmani, Slovin, Susan F, Wei, Joyce, Spriggs, David R, Dupont, Jakob, Allison, James P
Veröffentlicht 2010

Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of KOS-862 (Epothilone D) in Patients with Advanced Solid Tumors and Lymphoma

von Konner, Jason, Grisham, Rachel N., Park, Jae, O’Connor, Owen A., Cropp, Gillian, Johnson, Robert, Hannah, Alison L., Hensley, Martee L., Sabbatini, Paul, Miranov, Svetlana, Danishefsky, Samuel, Hyman, David, Spriggs, David R., Dupont, Jakob, Aghajanian, Carol
Veröffentlicht 2011

Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors

von Lockhart, A. Craig, Rothenberg, Mace L., Dupont, Jakob, Cooper, Wendy, Chevalier, Paul, Sternas, Lars, Buzenet, Giliane, Koehler, Elizabeth, Sosman, Jeffrey A., Schwartz, Lawrence H., Gultekin, David H., Koutcher, Jason A., Donnelly, Edwin F., Andal, Ric, Dancy, Isabelle, Spriggs, David R., Tew, William P.
Veröffentlicht 2010

Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Res...

von Ferrarotto, Renata, Mitani, Yoshitsugu, Diao, Lixia, Guijarro, Irene, Wang, Jing, Zweidler-McKay, Patrick, Bell, Diana, William, William N., Glisson, Bonnie S., Wick, Michael J., Kapoun, Ann M., Patnaik, Amita, Eckhardt, Gail, Munster, Pamela, Faoro, Leonardo, Dupont, Jakob, Lee, J. Jack, Futreal, Andrew, El-Naggar, Adel K., Heymach, John V.
Veröffentlicht in J Clin Oncol (2017)

A randomized phase II trial of nab‐paclitaxel and gemcitabine with tarextumab or placebo in patients with untreated metastatic pancreatic cancer

von Hu, Zishuo Ian, Bendell, Johanna C., Bullock, Andrea, LoConte, Noelle K., Hatoum, Hassan, Ritch, Paul, Hool, Hugo, Leach, Joseph W., Sanchez, James, Sohal, Davendra P. S., Strickler, John, Patel, Ravindranath, Wang‐Gillam, Andrea, Firdaus, Irfan, Yu, Kenneth H., Kapoun, Ann M., Holmgren, Eric, Zhou, Lei, Dupont, Jakob, Picozzi, Vincent, Sahai, Vaibhav, O'Reilly, Eileen M.
Veröffentlicht in Cancer Med (2019)