Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation

Por Aguirre, Jacob D., Dunkerley, Karen M., Mercier, Pascal, Shaw, Gary S.
Publicado no Proc Natl Acad Sci U S A (2017)

Impact of altered phosphorylation on loss of function of juvenile Parkinsonism–associated genetic variants of the E3 ligase parkin

Por Aguirre, Jacob D., Dunkerley, Karen M., Lam, Rica, Rusal, Michele, Shaw, Gary S.
Publicado no J Biol Chem (2018)

Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation

Por Condos, Tara EC, Dunkerley, Karen M, Freeman, E Aisha, Barber, Kathryn R, Aguirre, Jacob D, Chaugule, Viduth K, Xiao, Yiming, Konermann, Lars, Walden, Helen, Shaw, Gary S
Publicado no EMBO J (2018)