PrlA and PrlG suppressors reduce the requirement for signal sequence recognition.

per Flower, A M, Doebele, R C, Silhavy, T J
Publicat 1994

A phase I, open-label dose-escalation study of continuous treatment with BIBF 1120 in combination with paclitaxel and carboplatin as first-line treatment in patients with advanced...

per Doebele, R. C., Conkling, P., Traynor, A. M., Otterson, G. A., Zhao, Y., Wind, S., Stopfer, P., Kaiser, R., Camidge, D. R.
Publicat 2012

Exploratory analysis of the association of depth of response and survival in patients with metastatic non-small-cell lung cancer treated with a targeted therapy or immunotherapy

per McCoach, C E, Blumenthal, G M, Zhang, L, Myers, A, Tang, S, Sridhara, R, Keegan, P, Pazdur, R, Doebele, R C, Kazandjian, D
Publicat a Ann Oncol (2017)

Exploratory analysis of the association of depth of response and survival in patients with metastatic non-small-cell lung cancer treated with a targeted therapy or immunotherapy

per McCoach, C E, Blumenthal, G M, Zhang, L, Myers, A, Tang, S, Sridhara, R, Keegan, P, Pazdur, R, Doebele, R C, Kazandjian, D
Publicat a Ann Oncol (2019)

Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study

per Hong, D S, Bauer, T M, Lee, J J, Dowlati, A, Brose, M S, Farago, A F, Taylor, M, Shaw, A T, Montez, S, Meric-Bernstam, F, Smith, S, Tuch, B B, Ebata, K, Cruickshank, S, Cox, M C, Burris, H A, Doebele, R C
Publicat a Ann Oncol (2019)

HER2 exon 20 insertions in non-small-cell lung cancer are sensitive to the irreversible pan-HER receptor tyrosine kinase inhibitor pyrotinib

per Wang, Y., Jiang, T., Qin, Z., Jiang, J., Wang, Q., Yang, S., Rivard, C., Gao, G., Ng, T.L., Tu, M.M., Yu, H., Ji, H., Zhou, C., Ren, S., Zhang, J., Bunn, P., Doebele, R.C., Camidge, D.R., Hirsch, F.R.
Publicat a Ann Oncol (2019)

Oncogenic and drug sensitive NTRK1 rearrangements in lung cancer

per Vaishnavi, A., Capelletti, M., Le, A.T., Kako, S., Butaney, M., Ercan, D., Mahale, S., Davies, K.D., Aisner, D.L., Pilling, A.B., Berge, E.M., Kim, J., Sasaki, H., Park, S., Kryukov, G., Garraway, L.A., Hammerman, Peter S., Haas, J., Andrews, S.W., Lipson, D., Stephens, P.J., Miller, V.A., Varella-Garcia, M., Jänne, P.A., Doebele, R.C.
Publicat 2013

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

per Drilon, A., Laetsch, T.W., Kummar, S., DuBois, S.G., Lassen, U.N., Demetri, G.D., Nathenson, M., Doebele, R.C., Farago, A.F., Pappo, A.S., Turpin, B., Dowlati, A., Brose, M.S., Mascarenhas, L., Federman, N., Berlin, J., El-Deiry, W.S., Baik, C., Deeken, J., Boni, V., Nagasubramanian, R., Taylor, M., Rudzinski, E.R., Meric-Bernstam, F., Sohal, D.P.S., Ma, P.C., Raez, L.E., Hechtman, J.F., Benayed, R., Ladanyi, M., Tuch, B.B., Ebata, K., Cruickshank, S., Ku, N.C., Cox, M.C., Hawkins, D.S., Hong, D.S., Hyman, D.M.
Publicat a N Engl J Med (2018)