Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

Por Pawlyn, Charlotte, Melchor, Lorenzo, Murison, Alex, Wardell, Christopher P., Brioli, Annamaria, Boyle, Eileen M., Kaiser, Martin F., Walker, Brian A., Begum, Dil B., Dahir, Nasrin B., Proszek, Paula, Gregory, Walter M., Drayson, Mark T., Jackson, Graham H., Ross, Fiona M., Davies, Faith E., Morgan, Gareth J.
Publicado no Blood (2015)

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

Por Boyle, Eileen M, Proszek, Paula Z, Kaiser, Martin F, Begum, Dil, Dahir, Nasrin, Savola, Suvi, Wardell, Christopher P, Leleu, Xavier, Ross, Fiona M, Chiecchio, Laura, Cook, Gordon, Drayson, Mark T, Owen, Richard G, Ashcroft, John M, Jackson, Graham H, Anthony Child, James, Davies, Faith E, Walker, Brian A, Morgan, Gareth J
Publicado no Genes Chromosomes Cancer (2015)

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

Por Weinhold, Niels, Meissner, Tobias, Johnson, David C, Seckinger, Anja, Moreaux, Jérôme, Försti, Asta, Chen, Bowang, Nickel, Jolanta, Chubb, Daniel, Rawstron, Andrew C., Doughty, Chi, Dahir, Nasrin B., Begum, Dil B., Young, Kwee, Walker, Brian A., Hoffmann, Per, Nöthen, Marcus M., Davies, Faith E., Klein, Bernard, Goldschmidt, Hartmut, Morgan, Gareth J., Houlston, Richard S, Hose, Dirk, Hemminki, Kari
Publicado no Haematologica (2015)

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

Por Walker, Brian A, Wardell, Christopher P, Murison, Alex, Boyle, Eileen M, Begum, Dil B, Dahir, Nasrin M, Proszek, Paula Z, Melchor, Lorenzo, Pawlyn, Charlotte, Kaiser, Martin F, Johnson, David C, Qiang, Ya-Wei, Jones, John R, Cairns, David A, Gregory, Walter M, Owen, Roger G, Cook, Gordon, Drayson, Mark T, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J
Publicado no Nat Commun (2015)

The spectrum and clinical impact of epigenetic modifier mutations in myeloma

Por Pawlyn, Charlotte, Kaiser, Martin F, Heuck, Christoph, Melchor, Lorenzo, Wardell, Christopher P, Murison, Alex, Chavan, Shweta, Johnson, David C, Begum, Dil, Dahir, Nasrin, Proszek, Paula, Cairns, David A, Boyle, Eileen M, Jones, John R, Cook, Gordon, Drayson, Mark T, Owen, Roger G, Gregory, Walter M, Jackson, Graham H, Barlogie, Bart, Davies, Faith E, Walker, Brian A, Morgan, Gareth J
Publicado no Clin Cancer Res (2016)