Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors

por Halland, Nis, Schmidt, Friedemann, Weiss, Tilo, Saas, Joachim, Li, Ziyu, Czech, Jörg, Dreyer, Matthias, Hofmeister, Armin, Mertsch, Katharina, Dietz, Uwe, Strübing, Carsten, Nazare, Marc
Publicado en ACS Med Chem Lett (2014)

Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa)

por Schreuder, Herman, Liesum, Alexander, Lönze, Petra, Stump, Heike, Hoffmann, Holger, Schiell, Matthias, Kurz, Michael, Toti, Luigi, Bauer, Armin, Kallus, Christopher, Klemke-Jahn, Christine, Czech, Jörg, Kramer, Dan, Enke, Heike, Niedermeyer, Timo H. J., Morrison, Vincent, Kumar, Vasant, Brönstrup, Mark
Publicado en Sci Rep (2016)

Activation of Adenosine Monophosphate—Activated Protein Kinase Reduces the Onset of Diet‐Induced Hepatocellular Carcinoma in Mice

por Schmoll, Dieter, Ziegler, Nicole, Viollet, Benoit, Foretz, Marc, Even, Patrick C., Azzout‐Marniche, Dalila, Nygaard Madsen, Andreas, Illemann, Martin, Mandrup, Karen, Feigh, Michael, Czech, Jörg, Glombik, Heiner, Olsen, Jacob A., Hennerici, Wolfgang, Steinmeyer, Klaus, Elvert, Ralf, Castañeda, Tamara R., Kannt, Aimo
Publicado en Hepatol Commun (2020)

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

por Kannt, Aimo, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Swaminathan, Srinivasan, Hallur, Mahanandeesha Siddappa, Kristam, Rajendra, Elvert, Ralf, Czech, Jörg, Pfenninger, Anja, Rudolph, Christine, Schreuder, Herman, Chandrasekar, Devaraj Venkatapura, Mane, Vishal Subhash, Birudukota, Swarnakumari, Shaik, Shama, Zope, Bharat Ravindra, Burri, Raghunadha Reddy, Anand, Niranjan Naranapura, Thakur, Manish Kumar, Singh, Manvi, Parveen, Reejuana, Kandan, Saravanan, Mullangi, Ramesh, Yura, Takeshi, Gosu, Ramachandraiah, Ruf, Sven, Dhakshinamoorthy, Saravanakumar
Publicado en Sci Rep (2018)